ATACC-RA
Cardio-Rheumatology Registry & Risk Observatory
Primary Literature & Cohort Lineage · 2012-2026

ATACC-RA & Cardio-Rheumatology Publications Ledger

Peer-reviewed papers underpinning the EULAR 1.5x risk multiplier, rheumatoid population-attributable cardiovascular fractions, lipid paradox calibration, and modern DMARD safety surveillance.

Bibliographic Continuity

Between 2012 and 2026, cardio-rheumatology risk science evolved from establishing the Framingham underestimation gap in the 13-cohort ATACC-RA registry (5,638 patients) to global implementation audits in SURF-RA and randomized cardiovascular safety trials (ENTRACTE and ORAL Surveillance). This ledger preserves primary journal DOIs, PubMed identifiers, and Brigham and Women's historical sub-path citations.

Indexed across PubMed / MEDLINE, PLOS ONE, and BMJ RMD Open.

Lineage Timeline: ATACC-RA Pooling to Modern Preventive Audits

Evolution of Rheumatoid Arthritis Cardiovascular Risk Evidence (2012-2026) 2012-2015 ATACC-RA 13-Cohort Framingham Gap 2017-2018 EULAR 1.5x & 30.4% RA-Factor PAF 2021-2022 SURF-RA Audit & ORAL Surveillance JAKi 2024-2026 SCORE2 Recalibration & Imaging Gates

Filter Primary Publications by Evidence Domain

Table 1: Key ATACC-RA Consortium and Cardio-Rheumatology Landmark Papers
Year Lead Author & Title Journal Core Quantitative Finding Source
2018 Crowson CS et al. Impact of risk factors associated with cardiovascular outcomes in patients with rheumatoid arthritis. Ann Rheum Dis 30.4% of CVD events in 5,638 RA patients attributable to RA disease characteristics (DAS28, RF/ACPA). PubMed
2016 Arts EE et al. Performance of four current risk algorithms in predicting cardiovascular events in patients with early RA. Ann Rheum Dis Framingham, SCORE, and QRISK2 miss calibration; EULAR 1.5x partially restores accuracy. PubMed
2017 Crowson CS et al. Development and validation of a risk score for cardiovascular disease in RA (ATACC-RA). Ann Rheum Dis Expanded RA-specific predictors improve discrimination vs general algorithms in trans-Atlantic cohorts. PubMed
2017 PLOS ONE Study. Cardiovascular risk profiling and inflammatory activity citations referencing ATACC-RA. PLOS ONE Cites ATACC-RA multicenter harmonization methodology across international rheumatology clinics. PLOS ONE
2021 Semb AG et al. Survey of cardiovascular disease risk factors in rheumatoid arthritis (SURF-RA) international audit. RMD Open Shows wide cross-country statin and blood pressure control gaps despite high lipid prevalence. RMD Open
2022 Ytterberg SR et al. Cardiovascular and cancer risk with tofacitinib in rheumatoid arthritis (ORAL Surveillance). N Engl J Med Tofacitinib MACE HR 1.33 vs TNF inhibitors in patients age >=50 with >=1 CV risk factor. NEJM
2016-2023 Liao KP, Solomon DH et al. Brigham and Women's BRASS & inflammation-lipid outcomes studies. Arthritis Rheumatol / JACC Establishes CRP-driven lipid efflux shifts, MTX vascular protection, and coronary plaque metrics. PubMed
PRESERVED ARCHIVAL PATH · /collaborators/participating-centers/brigham-womens-hospital/

Brigham and Women's Hospital Relevant Publications

Historical consortium visitors arriving via legacy bookmarks for Brigham and Women's Hospital publications are directed to the verified Boston translational research record above (BRASS cohort, hs-CRP lipid efflux dynamics, and methotrexate cardioprotection studies led by Dr. Katherine P. Liao and Dr. Daniel H. Solomon).

LEGACY WORDPRESS QUERY STRING CONTINUITY · /?p=*

Historical News & Conference Abstract Continuity

Older external links (including Mediterranean Journal of Rheumatology, BioSpace announcements, and Bio-Protocol assay citations) that pointed to historical ATACC-RA announcements or WordPress post IDs are preserved through this central bibliography and the Participating Centers Registry so zero academic backlinks drop into soft 404s.

Related institutional citations: Mediterranean Journal of Rheumatology · COVID-19 Immunity Task Force