Publications related to CVD and RA by the collaborators in the ATACC-RA consortium

  1. Ahmadi N, Hajsadeghi F, Choi TY, Flores F, Munoz S, Ebrahimi R, Budoff M, Karpouzas G. Relation of Pulse Wave Velocity Measured by Computed Tomography Angiography with Vulnerable Characteristics of Coronary Plaque Composition among Patients with and without Rheumatoid Arthritis. J Am Coll Cardiol 2011; 57: 49A.
  2. Akkara Veetil BM, Myasoedova E, Matteson EL, Gabriel SE, Crowson CS. Use of lipid-lowering agents in rheumatoid arthritis: a population-based cohort study. J Rheumatol. 2013 Jul; 40(7):1082-8. Epub 2013 May 01. PMID:23637326. PMCID:3891914. DOI:10.3899/jrheum.121302.
  3. Arts E , Popa C, Den Broeder AA, Semb AG, Kitas G, van Riel P, Fransen J. Predicting the risk of cardiovascular disease in rheumatoid arthritis patients with five currently used risk alagorithms. Ann Rheum Dis 2014 (January 1.) online doi: 10.1136/annrheumdis-2013-204024
  4. Arts EE, Popa C, Den Broeder AA, Semb AG, Toms T, Kitas GD, van Riel PL, Fransen J. Performance of four current risk algorithms in predicting cardiovascular events in patients with early rheumatoid arthritis. Ann Rheum Dis. 2014 Jan 3. doi: 10.1136/annrheumdis-2013-204024. [Epub ahead of print] PubMed PMID: 24389293.
  5. Aubry MC, Maradit-Kremers H, Reinalda MS, Crowson CS, Edwards WD, Gabriel SE. Differences in atherosclerotic coronary heart disease between subjects with and without rheumatoid arthritis.  J Rheumatol. 2007 May; 34(5):937-42.  PMID:17361987.
  6. Bacani AK, Gabriel SE, Crowson CS, Heit JA, Matteson EL. Noncardiac vascular disease in rheumatoid arthritis: increase in venous thromboembolic events?  Arthritis Rheum. 2012 Jan; 64(1):53-61.  PMID:21905005. PMCID:3474372. DOI:10.1002/art.33322.
  7. Bacon PA, Raza K, Banks MJ, Townend J, Kitas GD. The role of endothelial cell dysfunction in the cardiovascular mortality of RA. Int Rev Immunol. 2002 Jan-Feb;21(1):1-17. Review. PubMed PMID: 12187841.
  8. Bacon PA, Stevens RJ, Carruthers DM, Young SP, Kitas GD. Accelerated atherogenesis in autoimmune rheumatic diseases. Autoimmun Rev. 2002 Dec;1(6):338-47. Review. PubMed PMID: 12848989.
  9. Bacons PA, Kitas GD. The significance of vascular inflammation in rheumatoid arthritis. Ann Rheum Dis. 1994 Oct;53(10):621-3. Review. PubMed PMID: 7979572; PubMed Central PMCID: PMC1005422.
  10. Bamias G, Stamatelopoulos K, Zampeli E, Protogerou A, Sigala F, Papamichael C, Christopoulos P, Kitas GD, Sfikakis PP. Circulating levels of TNF-like cytokine 1A correlate with the progression of atheromatous lesions in patients with rheumatoid arthritis. Clin Immunol. 2013 May;147(2):144-50.
  11. Bamias G, Stamatelopoulos K, Zampeli E, Protogerou A, Sigala F, Papamichael C, Christopoulos P, Kitas GD, Sfikakis PP. Circulating levels of TNF-like cytokine 1A correlate with the progression of atheromatous lesions in patients with rheumatoid arthritis. Clin Immunol. 2013 May;147(2):144-50. doi: 10.1016/j.clim.2013.03.002. Epub 2013 Mar 26. PubMed PMID: 23598291.
  12. Banks M, Kitas G. Patients’ physical disability may influence doctors’ perceptions of suitability for risk assessment of CHD. BMJ. 1999 Nov 6;319(7219):1266-7. PubMed PMID: 10550104; PubMed Central PMCID: PMC1117033.
  13. Barbhaiya M, Solomon DH. Rheumatoid arthritis and cardiovascular disease: an update on treatment issues. Curr Opin Rheumatol. May 2013;25(3):317-324.
  14. Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons LJ; Wellcome Trust Case Control Consortium; YEAR Consortium; BIRAC Consortium, Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Worthington J. Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet. 2008 Oct;40(10):1156-9. doi: 10.1038/ng.218. Epub 2008 Sep 14. PubMed PMID: 18794857; PubMed Central PMCID: PMC2662493.
  15. Bayley R, Kite KA, McGettrick HM, Smith JP, Kitas GD, Buckley CD, Young SP. The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals. Ann Rheum Dis. 2014 Mar 24. doi: 10.1136/annrheumdis-2013-204796. [Epub ahead of print] PubMed PMID: 24665115.
  16. Bengtsson C, Öhman ML, Nived O, Rantapää Dahlqvist S. Cardiovascular event in Systemic Lupus Erythematosus in northern Sweden – Incidence and predictors in a 7-year follow up study. Lupus. 2012 Apr;21(4):452-9. doi: 10.1177/0961203311425524. Epub 2011 Nov 7
  17. Berglund S, Södergren A, Wållberg-Jonsson S, Rantapää-Dahlqvist S Cardiovascular event in rheumatoid arthritis is predicted by homocysteine – a six- year follow-up study. Clin Exp Rheumatol. 2009 Sep-Oct;27(5):822-5
  18. Bevan RJ, Durand MF, Hickenbotham PT, Kitas GD, Patel PR, Podmore ID, Griffiths HR, Waller HL, Lunec J. Validation of a novel ELISA for measurement of MDA-LDL in human plasma. Free Radic Biol Med. 2003 Sep 1;35(5):517-27. PubMed PMID: 12927601.
  19. Bluett J, Ibrahim I, Plant D, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD; BRAGGSS, Barton A. Association of a complement receptor 1 gene variant with baseline erythrocyte sedimentation rate levels in patients starting anti-TNF therapy in a UK rheumatoid arthritis cohort: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort. Pharmacogenomics J. 2014 Apr;14(2):171-5. doi: 10.1038/tpj.2013.26. Epub 2013 Jul 16. PubMed PMID: 23856853; PubMed Central PMCID: PMC3965567.
  20. Booth DA, Treharne GJ, Kitas GD, Kumar S. Avoidance of unhealthy fattening:  a longstanding proposal. Appetite. 2007 Mar;48(2):129-34. Epub 2006 Oct 19. Review. PubMed PMID: 17055110.
  21. Burr ML, Naseem H, Hinks A, Eyre S, Gibbons LJ, Bowes J, Wilson AG, Maxwell J, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Thomson W, Worthington J; BIRAC Consortium; YEAR Consortium, Barton A. PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population. Ann Rheum Dis. 2010 Apr;69(4):666-70. doi: 10.1136/ard.2009.111294. Epub 2009 May 25. Erratum in: Ann Rheum Dis. 2011 Aug;70(8):1519. PubMed PMID: 19470526; PubMed Central PMCID: PMC2927647.
  22. Central PMCID: PMC3804609.
  23. Choy E, Ganeshalingam K, Semb AG, Szekanecz Z, Nurmohamed M. Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors, and the impact of treatment. J Rheumatol 2014 (in press)
  24. Choy EH, Smith CM, Farewell V, Walker D, Hassell A, Chau L, Scott DL; CARDERA (Combination Anti-Rheumatic Drugs in Early Rheumatoid Arhritis) Trial Group. Factorial randomised controlled trial of glucocorticoids and combination disease modifying drugs in early rheumatoid arthritis. Ann Rheum Dis. 2008 May;67(5):656-63. Epub 2007 Sep 3. PubMed PMID: 17768173.
  25. Corrales A, González-Juanatey C, Peiró ME, Blanco R, Llorca J, González-Gay MA. Carotid ultrasound is useful for the cardiovascular risk stratification of patients with rheumatoid arthritis: results of a population-based study. Ann Rheum Dis. 2014 Apr;73(4):722-7. doi: 10.1136/annrheumdis-2012-203101. Epub 2013 Mar 16. PubMed PMID: 23505241.
  26. Corrales A, Parra JA, González-Juanatey C, Rueda-Gotor J, Blanco R, Llorca J, González-Gay MA. Cardiovascular risk stratification in rheumatic diseases: carotid ultrasound is more sensitive than Coronary Artery Calcification Score to detect subclinical atherosclerosis in patients with rheumatoid arthritis. Ann Rheum Dis. 2013 Nov 1;72(11):1764-70. doi: 10.1136/annrheumdis-2013-203688. Epub 2013 Jul 13. PubMed PMID: 23852762.
  27. Crowson CS, Gabriel SE. Towards improving cardiovascular risk management in patients with rheumatoid arthritis: the need for accurate risk assessment.  Ann Rheum Dis. 2011 May; 70(5):719-21. Epub 2011 Feb 22.  PMID:21345812. PMCID:3907170. DOI:10.1136/ard.2010.145482.
  28. Crowson CS, Liao KP, Davis JM 3rd, Solomon DH, Matteson EL, Knutson KL, Hlatky MA, Gabriel SE. Rheumatoid arthritis and cardiovascular disease. Am Heart J. 2013 Oct; 166(4):622-628.e1. Epub 2013 Aug 29. PMID:24093840. PMCID:3890244. DOI:10.1016/j.ahj.2013.07.010.
  29. Crowson CS, Matteson EL, Roger VL, Therneau TM, Gabriel SE. Usefulness of risk scores to estimate the risk of cardiovascular disease in patients with rheumatoid arthritis.  Am J Cardiol. 2012 Aug 1; 110(3):420-4. Epub 2012 Apr 20.  PMID:22521305. PMCID:3398213. DOI:10.1016/j.amjcard.2012.03.044.
  30. Crowson CS, Myasoedova E, Davis JM 3rd, Matteson EL, Roger VL, Therneau TM, Fitz-Gibbon P, Rodeheffer RJ, Gabriel SE. Increased prevalence of metabolic syndrome associated with rheumatoid arthritis in patients without clinical cardiovascular disease.  J Rheumatol. 2011 Jan; 38(1):29-35. Epub 2010 Oct 15.  PMID:20952464. PMCID:3014403. DOI:10.3899/jrheum.100346.
  31. Crowson CS, Myasoedova E, Davis JM 3rd, Roger VL, Karon BL, Borgeson D, Rodeheffer RJ, Therneau TM, Gabriel SE. Use of B-type natriuretic peptide as a screening tool for left ventricular diastolic dysfunction in rheumatoid arthritis patients without clinical cardiovascular disease.  Arthritis Care Res (Hoboken). 2011 May; 63(5):729-34.  PMID:21225672. PMCID:3091972. DOI:10.1002/acr.20425.
  32. Crowson CS, Nicola PJ, Maradit Kremers H, O’Fallon WM, Therneau TM, Jacobsen SJ, Roger VL, Ballman KV, Gabriel SE. How much of the increased incidence of heart failure in rheumatoid arthritis is attributable to traditional cardiovascular risk factors and ischemic heart disease?  Arthritis Rheum. 2005 Oct; 52(10):3039-44.  PMID:16200583.
  33. Crowson CS, Therneau TM, Davis JM 3rd, Roger VL, Matteson EL, Gabriel SE. Brief report: accelerated aging influences cardiovascular disease risk in rheumatoid arthritis. Arthritis Rheum. 2013 Oct; 65(10):2562-6. PMID:23818136. PMCID:3966134. DOI:10.1002/art.38071.
  34. Crowson CS. Rheumatoid arthritis and heart disease: the chicken and the egg?  J Intern Med. 2010 Dec; 268(6):552-4. Epub 2010 Nov 05.  PMID:21054586. DOI:10.1111/j.1365-2796.2010.02296.x.
  35. Cutolo M, Kitas GD, van Riel PL. Burden of disease in treated rheumatoid arthritis patients: going beyond the joint. Semin Arthritis Rheum. 2014 Feb;43(4):479-88. doi: 10.1016/j.semarthrit.2013.08.004. Epub 2013 Sep 27. PubMed PMID: 24080116.
  36. Daoussis D, Kitas GD. Uric acid and cardiovascular risk in rheumatoid arthritis. Rheumatology (Oxford). 2011 Aug;50(8):1354-5. doi: 10.1093/rheumatology/keq388. Epub 2010 Nov 28. PubMed PMID: 21115462.
  37. Daoussis D, Panoulas V, Toms T, John H, Antonopoulos I, Nightingale P, Douglas KM, Klocke R, Kitas GD. Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis. Arthritis Res Ther. 2009;11(4):R116. doi: 10.1186/ar2775. Epub 2009 Jul 24. PubMed PMID: 19630964; PubMed Central PMCID: PMC2745798.
  38. Daoussis D, Panoulas VF, Antonopoulos I, John H, Toms TE, Wong P, Nightingale P, Douglas KM, Kitas GD. Cardiovascular risk factors and not disease  activity, severity or therapy associate with renal dysfunction in patients with rheumatoid arthritis. Ann Rheum Dis. 2010 Mar;69(3):517-21. doi: 10.1136/ard.2008.105049. Epub 2009 Mar 10. PubMed PMID: 19279016.
  39. Daoussis D, Panoulas VF, John H, Toms TE, Antonopoulos I, Treharne G, Nightingale P, Douglas KM, Kitas GD. Microalbuminuria in rheumatoid arthritis in the post penicillamine/gold era: association with hypertension, but not therapy or inflammation. Clin Rheumatol. 2011 Apr;30(4):477-84. doi: 10.1007/s10067-010-1446-y. Epub 2010 Apr 16. PubMed PMID: 20396921.
  40. Davis JM 3rd, Knutson KL, Strausbauch MA, Crowson CS, Therneau TM, Wettstein PJ, Roger VL, Matteson EL, Gabriel SE. A signature of aberrant immune responsiveness identifies myocardial dysfunction in rheumatoid arthritis.  Arthritis Rheum. 2011 Jun; 63(6):1497-506.  PMID:21384332. PMCID:3106129. DOI:10.1002/art.30323.
  41. Davis JM 3rd, Maradit Kremers H, Crowson CS, Nicola PJ, Ballman KV, Therneau TM, Roger VL, Gabriel SE. Glucocorticoids and cardiovascular events in rheumatoid arthritis: a population-based cohort study.  Arthritis Rheum. 2007 Mar; 56(3):820-30.  PMID:17330254.
  42. Davis JM 3rd, Roger VL, Crowson CS, Kremers HM, Therneau TM, Gabriel SE. The presentation and outcome of heart failure in patients with rheumatoid arthritis differs from that in the general population.  Arthritis Rheum. 2008 Sep; 58(9):2603-11.  PMID:18759286. PMCID:2631416. DOI:10.1002/art.23798.
  43. Dessein PH, Christian BF, Solomon A. Application of the Joint British Societies’ guidelines on the prevention of cardiovascular disease in public and private health care patients with rheumatoid arthritis. J Rheumatol 2010;37:201-202.
  44. Dessein PH, Christian BF, Solomon A. Which are the determinants of dyslipidemia in rheumatoid arthritis and does socioeconomic status matter in this context? J Rheumatol 2009;36:1357-1361.
  45. Dessein PH, Christian BF, Woodiwiss AJ, Norton GR, Solomon A.  Public healthcare attendance associates with enhanced conventional and non-conventional atherosclerotic cardiovascular disease risk burdens in established rheumatoid arthritis. Clin Exp Rheumatol 2010;28:230-237.
  46. Dessein PH, Joffe BI, Singh S. Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis. Ann Rheum Dis 2005;64:178-179.
  47. Dessein PH, Joffe BI, Singh S. Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis. Arthritis Res Ther 2005;7:R634-R643.
  48. Dessein PH, Joffe BI, Stanwix A, Botha AS, Moomal Z. The acute phase response does not fully predict the presence of insulin resistance and dyslipidemia in inflammatory arthritis. J Rheumatol 2002;29:462-466.
  49. Dessein PH, Joffe BI, Stanwix AE, Christian BF, Veller M. Glucocorticoids and insulin sensitivity in rheumatoid arthritis. J Rheumatol May 2004;31:867-874.
  50. Dessein PH, Joffe BI, Stanwix AE. Effects of disease modifying agents and dietary intervention on insulin resistance and dyslipidemia in inflammatory arthritis – a pilot study.  Arthritis Res 2002;4:R12.
  51. Dessein PH, Joffe BI, Stanwix AE. High sensitivity C-reactive protein as a disease activity marker in rheumatoid arthritis. J Rheumatol June 2004;31:1095-1097.
  52. Dessein PH, Joffe BI, Stanwix AE. Inflammation, insulin resistance, and aberrant lipid metabolism as cardiovascular risk factors in rheumatoid arthritis. J Rheumatol 2003;30:1403-1405.
  53. Dessein PH, Joffe BI, Stanwix AE. Should we measure insulin sensitivity in rheumatoid arthritis. Semin Arthritis Rheum 2005;35:5-7.
  54. Dessein PH, Joffe BI, Stanwix AE. Subclinical hypothyroidism is associated with insulin resistance in rheumatoid arthritis. Thyroid 2004;14:443-446.
  55. Dessein PH, Joffe BI, Veller MG, Stevens BA, Tobias M, Reddi K, Stanwix AE. Traditional and non-traditional cardiovascular risk factors are associated with atherosclerosis in rheumatoid arthritis. J Rheumatol 2005;32:435-442.
  56. Dessein PH, Joffe BI. Insulin resistance and impaired ß-cell function in rheumatoid arthritis. Arthritis Rheum 2006;54: 2765-2775.
  57. Dessein PH, Joffe BI. Suppression of circulating interleukin-6 concentrations is associated with decreased endothelial activation in rheumatoid arthritis. Clin Exp Rheumatol 2006;24:161-167.
  58. Dessein PH, Joffe BI. When is a patient with rheumatoid arthritis at risk for cardiovascular disease? J Rheumatol 2006;33:201-203.
  59. Dessein PH, López-Mejias R, González-Juanatey C, Genre F, Miranda-Filloy JA, Llorca J, González-Gay MA. Independent Relationship of Osteoprotegerin Concentrations with Endothelial Activation and Carotid Atherosclerosis in Patients with Severe Rheumatoid Arthritis. J Rheumatol 2014;41:429-436..
  60. Dessein PH, López-Mejias R, González-Juanatey C, Genre F, Miranda-Filloy JA, Llorca J, González-Gay MA. Independent relationship of osteoprotegerin concentrations with endothelial activation and carotid atherosclerosis in patients with severe rheumatoid arthritis. J Rheumatol. 2014 Mar;41(3):429-36. doi: 10.3899/jrheum.131037. Epub 2014 Feb 1. PubMed PMID: 24488413.
  61. Dessein PH, Norton GR, Badenhorst M, Woodiwiss AJ, Solomon A. Rheumatoid arthritis impacts on the independent relationships between circulating adiponectin concentrations and cardiovascular metabolic risk. Mediators Inflamm 2013;2013:461849.doi.10.1155/2013/461849.
  62. Dessein PH, Norton GR, Joffe BI, Abdool-Carrim AT, Woodiwiss AJ, Solomon A. Metabolic cardiovascular risk burden and atherosclerosis in African black and Caucasian women with rheumatoid arthritis: a cross-sectional study. Clin Exp Rheumatol 2013;31:53-61.
  63. Dessein PH, Norton GR, Woodiwiss AJ, Joffe BI, Solomon A. Independent role of conventional cardiovascular risk factors as predictors of C-reactive protein concentrations in rheumatoid arthritis. J Rheumatol 2007;34:681-688.
  64. Dessein PH, Norton GR, Woodiwiss AJ, Joffe BI, Wolfe F. Influence of nonclassical cardiovascular risk factors on the accuracy of predicting subclinical atherosclerosis in rheumatoid arthritis. J Rheumatol 2007;34:943-951.
  65. Dessein PH, Norton GR, Woodiwiss AJ, Solomon A. Independent relationship between circulating resistin concentrations and endothelial activation in rheumatoid arthritis. Ann Rheum Dis 2013;72:1586-1588
  66. Dessein PH, Norton GR, Woodiwiss AJ, Tsang L. Age impacts on the independent relationships of leptin with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in black and white patients with rheumatoid arthritis: a cross-sectional study. Rheumatol Int 2014;34:329-339.
  67. Dessein PH, Norton GR. Should patients with RA be aggressively monitored for hypertension? Nature Clin Pract Rheumatol 2008;4:18-19.
  68. Dessein PH, Semb AG. Could cardiovascular disease risk stratification and management in rheumatoid arthritis be enhanced? Ann Rheum Dis 2013;72:1743-1746.
  69. Dessein PH, Semb AG. Could cardiovascular disease risk stratification and management in rheumatoid arthritis be enhanced? Editorial Ann Rheum Dis 2013 2013; 72(11):1743-6
  70. Dessein PH, Solomon A, Woodiwiss AJ, Norton GR, Tsang L, Gonzalez-Gay MA. Marked Independent Relationship between Circulating Interleukin-6 Concentrations and Endothelial Activation in Rheumatoid Arthritis.  Mediators Inflamm 2013 doi.10.1155/2013/510243.
  71. Dessein PH, Solomon A, Woodiwiss AJ, Norton GR, Tsang L, Gonzalez-Gay MA. Marked independent relationship between circulating interleukin-6 concentrations and endothelial activation in rheumatoid arthritis. Mediators Inflamm. 2013;2013:510243. doi: 10.1155/2013/510243. Epub 2013 Dec 21. PubMed PMID: 24453423; PubMed Central PMCID: PMC3880757.
  72. Dessein PH, Solomon A. Towards the elucidation of the true impact of adipocytokines on cardiovascular risk in rheumatoid arthritis.  Arthritis Res Ther 2013;15:127.
  73. Dessein PH, Stanwix AE, Joffe BI. Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis. Arthritis Res 2002;4:R5.
  74. Dessein PH, Stanwix AE. Inflammatory arthritis and cardiovascular disease may share a common predisposition. Rheumatology 2001;40:703-704.
  75. Dessein PH, Stanwix AE. Steroids and myocardial infarction in rheumatoid arthritis. Reply to Dr AS Russell. J Rheumatol 2005;32:196-197.
  76. Dessein PH, Tobias M, Veller MG. Metabolic syndrome and subclinical atherosclerosis in rheumatoid arthritis. J Rheumatol 2006;33:2425-2432.
  77. Dessein PH, Tsang L, Norton GR, Woodiwiss AJ, Solomon A. Retinol binding protein 4 concentrations relate to enhanced atherosclerosis in obese patients with rheumatoid arthritis. PLoS One 2014;9:e92738. doi:10.137/journal.pone.0092739. eCollection 2014.
  78. Dessein PH, Woodiwiss AJ, Joffe BI, Norton GR. Aminotransferases are associated with insulin resistance and atherosclerosis in rheumatoid arthritis. BMC Cardiovasc Disord 2007;7(1):31.
  79. Dessein PH, Woodiwiss AJ, Norton GR, Solomon A. Rheumatoid arthritis is associated with reduced adiposity but not with unfavorable major cardiovascular risk factor profiles and enhanced carotid atherosclerosis in black Africans from a developing population: a cross-sectional study. Arthritis Res Ther 2013;15: R96 [Epub ahead of print].
  80. Dessein PH, Woodiwiss AJ, Norton GR, Tsang L, Solomon A. Independent associations of total and high molecular weight adiponectin with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in black and white patients with rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther 2013;15:R128.
  81. Dessein PH. Vitamin D replacement therapy: a promising adjunct in cardiovascular risk management among patients with rheumatoid arthritis? J Rheumatol 2013;40:1463-1465.
  82. Dimitroulas T, Douglas KM, Panoulas VF, Toms T, Smith JP, Treharne GJ, Nightingale P, Hodson J, Kitas GD. Derangement of hemostasis in rheumatoid arthritis: association with demographic, inflammatory and metabolic factors. Clin Rheumatol. 2013 Sep;32(9):1357-64. doi: 10.1007/s10067-013-2283-6. Epub 2013 May 15. PubMed PMID: 23673438.
  83. Dimitroulas T, Douglas KM, Smith J, Panoulas VF, Kitas GD. Lack of association between polymorphisms of thrombogenic genes and disease susceptibility in rheumatoid arthritis. Rheumatol Int. 2013 Sep;33(9):2429-32. doi: 10.1007/s00296-012-2392-6. Epub 2012 Mar 31. PubMed PMID: 22466403.
  84. Dimitroulas T, Giannakoulas G, Karvounis H, Garyfallos A, Settas L, Kitas G. B-type natriuretic peptide in rheumatic diseases: a cardiac biomarker or a sophisticated acute phase reactant? Autoimmun Rev. 2012 Oct;11(12):837-43. doi: 10.1016/j.autrev.2012.02.018. Epub 2012 Feb 28. Review. PubMed PMID: 22401930.
  85. Dimitroulas T, Giannakoulas G, Karvounis H, Garyfallos A, Settas L, Kitas GD. Micro- and macrovascular treatment targets in scleroderma heart disease. Curr Pharm Des. 2014;20(4):536-44. PubMed PMID: 23565639.
  86. Dimitroulas T, Giannakoulas G, Karvounis H, Settas L, Kitas GD. Biomarkers in systemic sclerosis-related pulmonary arterial hypertension. Curr Vasc Pharmacol. 2011 Mar;9(2):213-9. Review. PubMed PMID: 21143174.
  87. Dimitroulas T, Giannakoulas G, Karvounis H, Settas L, Kitas GD. Systemic sclerosis-related pulmonary hypertension: unique characteristics and future treatment targets. Curr Pharm Des. 2012;18(11):1457-64. Review. PubMed PMID: 22364130.
  88. Dimitroulas T, Mavrogeni S, Kitas GD. Imaging modalities for the diagnosis of pulmonary hypertension in systemic sclerosis. Nat Rev Rheumatol. 2012 Feb 7;8(4):203-13. doi: 10.1038/nrrheum.2012.2. Review. PubMed PMID: 22310183.
  89. Dimitroulas T, Sandoo A, Kitas GD. Asymmetric dimethylarginine as a surrogate marker of endothelial dysfunction and cardiovascular risk in patients with systemic rheumatic diseases. Int J Mol Sci. 2012 Sep 26;13(10):12315-35. doi: 10.3390/ijms131012315. PubMed PMID: 23202900; PubMed Central PMCID: PMC3497274.
  90. Dimitroulas T, Sandoo A, Smith JP, Kitas GD. Asymmetric dimethylarginine is not associated with subendocardial viability ratio in Rheumatoid Arthritis. Int J Cardiol. 2014 Mar 1;172(1):285-6. doi: 10.1016/j.ijcard.2013.12.235. Epub 2014 Jan 10. PubMed PMID: 24447745.
  91. Dimitroulas T, Sandoo A, Veldhuijzen van Zanten JJ, Smith JP, Hodson J, Metsios GS, Stavropoulos-Kalinoglou A, Kitas GD. Predictors of asymmetric dimethylarginine levels in patients with rheumatoid arthritis: the role of insulin resistance. Scand J Rheumatol. 2013;42(3):176-81. doi: 10.3109/03009742.2012.747627. Epub 2013 Jan 14. PubMed PMID: 23311682.
  92. Douglas KM, Pace AV, Treharne GJ, Saratzis A, Nightingale P, Erb N, Banks MJ, Kitas GD. Excess recurrent cardiac events in rheumatoid arthritis patients with acute coronary syndrome. Ann Rheum Dis. 2006 Mar;65(3):348-53. Epub 2005 Aug 3. PubMed PMID: 16079169; PubMed Central PMCID: PMC1798075.
  93. Dysfunctional proinflammatory high-density lipoproteins confer increased risk of atherosclerosis in women with systemic lupus erythematosus.McMahon M, Grossman J, Skaggs B, Fitzgerald J, Sahakian L, Ragavendra N, Charles-Schoeman C, Watson K, Wong WK, Volkmann E, Chen W, Gorn A, Karpouzas G, Weisman M, Wallace DJ, Hahn BH. Arthritis Rheum. 2009 Aug;60(8):2428-37. doi: 10.1002/art.24677.
  94. El-Gabalawy HS, Robinson DB, Hart D, Elias B, Markland J, Peschken CA, SmolikI, Montes-Aldana G, Schroeder M, Fritzler MJ, Cheang M, Oen K. Immunogeneticrisks of anti-cyclical citrullinated peptide antibodies in a North AmericanNative population with rheumatoid arthritis and their first-degree relatives. JRheumatol. 2009 Jun;36(6):1130-5. doi: 10.3899/jrheum.080855. Epub 2009 May 1. PubMed PMID: 19411392.
  95. El-Gabalawy HS, Robinson DB, Smolik I, Hart D, Elias B, Wong K, Peschken CA, Hitchon CA, Li X, Bernstein CN, Newkirk MM, Fritzler MJ. Familial clustering ofthe serum cytokine profile in the relatives of rheumatoid arthritis patients.Arthritis Rheum. 2012 Jun;64(6):1720-9. doi: 10.1002/art.34449. Epub 2012 Feb 21.PubMed PMID: 22354869.
  96. Erb N, Kitas GD. Homocysteine modulation as a reason for continuous folic acid supplementation in methotrexate-treated rheumatoid arthritis patients. Rheumatology (Oxford). 2001 Jun;40(6):715-6. PubMed PMID: 11426040.
  97. Erb N, Pace AV, Douglas KM, Banks MJ, Kitas GD. Risk assessment for coronary heart disease in rheumatoid arthritis and osteoarthritis. Scand J Rheumatol. 2004;33(5):293-9. PubMed PMID: 15513676.
  98. Exley AR, Bacon PA, Luqmani RA, Kitas GD, Carruthers DM, Moots R. Examination of disease severity in systemic vasculitis from the novel perspective of damage using the vasculitis damage index (VDI). Br J Rheumatol. 1998 Jan;37(1):57-63. PubMed PMID: 9487252.
  99. Exley AR, Bacon PA, Luqmani RA, Kitas GD, Gordon C, Savage CO, Adu D. Development and initial validation of the Vasculitis Damage Index for the standardized clinical assessment of damage in the systemic vasculitides. Arthritis Rheum. 1997 Feb;40(2):371-80. PubMed PMID: 9041949.
  100. Exley AR, Carruthers DM, Luqmani RA, Kitas GD, Gordon C, Janssen BA, Savage CO, Bacon PA. Damage occurs early in systemic vasculitis and is an index of outcome. QJM. 1997 Jun;90(6):391-9. PubMed PMID: 9205677.
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  168. González-Gay MA, González-Juanatey C, Miranda-Filloy JA, García-Unzueta MT, Llorca J. Lack of association between flow-mediated endothelium-dependent vasodilatation and biomarkers of endothelial dysfunction in patients with severe rheumatoid arthritis. Rheumatol Int. 2012 Dec;32(12):4071-2. doi: 10.1007/s00296-011-2254-7. Epub 2011 Nov 6. PubMed PMID: 22057149.
  169. González-Gay MA, González-Juanatey C, Miranda-Filloy JA, Llorca J. The potential effect of TNF-α antagonist therapy in rheumatoid arthritis may depend on the degree and severity of insulin resistance before the onset of this therapy. Horm Metab Res. 2012 Jun;44(7):558-9. doi: 10.1055/s-0032-1308972. Epub 2012 Apr 5. PubMed PMID: 22488517.
  170. Gonzalez-Gay MA, Gonzalez-Juanatey C, Miranda-Filloy JA, Martin J, Garcia-Unzueta MT, Llorca J. Response to ‘Infliximab therapy increases body fat mass in early rheumatoid arthritis independently of changes in disease activity and levels of leptin and adiponectin: a randomized study over 21 months’. Arthritis Res Ther. 2011 Apr 27;13(2):404. doi: 10.1186/ar3301. PubMed PMID: 21542887; PubMed Central PMCID: PMC3132047.
  171. Gonzalez-Gay MA, Gonzalez-Juanatey C, Miranda-Filloy JA, Martin J, Llorca J. Role of carotid ultrasonography in the evaluation of cardiovascular risk in patients with rheumatoid arthritis. Arthritis Res Ther. 2010;12(6):409. doi: 10.1186/ar3186. Epub 2010 Dec 16. PubMed PMID: 21205284; PubMed Central PMCID: PMC3046517.
  172. Gonzalez-Gay MA, Gonzalez-Juanatey C, Ollier WE. Endothelial dysfunction in rheumatoid arthritis: influence of HLA-DRB1 alleles. Autoimmun Rev. 2004 Jun;3(4):301-4. Review. PubMed PMID: 15246026.
  173. Gonzalez-Gay MA, Gonzalez-Juanatey C, Piñeiro A, Garcia-Porrua C, Testa A, Llorca J. High-grade C-reactive protein elevation correlates with accelerated atherogenesis in patients with rheumatoid arthritis. J Rheumatol. 2005 Jul;32(7):1219-23. PubMed PMID: 15996055.
  174. Gonzalez-Gay MA, Gonzalez-Juanatey C, Rodriguez-Rodriguez L, Miranda-Filloy JA, Martin J, Llorca J. Lack of association between adipokines and ghrelin and carotid intima-media thickness in patients with severe rheumatoid arthritis. Clin Exp Rheumatol. 2011 Mar-Apr;29(2):358-9. Epub 2011 Apr 19. PubMed PMID: 21418784.
  175. Gonzalez-Gay MA, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Dierssen T, Llorca J. Role of asymptomatic hyperuricemia and serum uric acid levels in the pathogenesis of subclinical atherosclerosis in psoriatic arthritis: comment on the article by Chen et al. Arthritis Rheum. 2009 Jun 15;61(6):856-7; author reply 857-8. doi: 10.1002/art.24584. PubMed PMID: 19479685.
  176. Gonzalez-Gay MA, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Gomez-Acebo I, Miranda-Filloy JA, Paz-Carreira J, Martin J, Llorca J. Asymptomatic hiperuricemia and serum uric acid concentration correlate with subclinical atherosclerosis in psoriatic arthritis patients without clinically evident cardiovascular disease. Semin Arthritis Rheum. 2009 Dec;39(3):157-62. doi: 10.1016/j.semarthrit.2008.06.001. Epub 2008 Aug 22. PubMed PMID: 18722649.
  177. Gonzalez-Gay MA, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Llorca J. The use of carotid ultrasonography in the assessment of subclinical atherosclerosis and the paradoxical effect of corticosteroids on atherosclerosis in patients with rheumatoid arthritis. Clin Exp Rheumatol. 2009 Jan-Feb;27(1 Suppl 52):S141; author reply S141. PubMed PMID: 19646362.
  178. Gonzalez-Gay MA, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Martin J, Llorca J. Carotid intima-media thickness and endothelial function: useful surrogate markers for establishing cardiovascular risk in patients with inflammatory rheumatic disease. Arthritis Res Ther. 2008;10(3):403; author reply 404. doi: 10.1186/ar2409. Epub 2008 May 16. PubMed PMID: 18510782; PubMed Central PMCID: PMC2483434.
  179. Gonzalez-Gay MA, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Martin J, Llorca J. Endothelial dysfunction, carotid intima-media thickness, and accelerated atherosclerosis in rheumatoid arthritis. Semin Arthritis Rheum. 2008 Oct;38(2):67-70. doi: 10.1016/j.semarthrit.2008.02.001. Epub 2008 Apr 18. PubMed PMID: 18395772.
  180. Gonzalez-Gay MA, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Miranda-Filloy JA, Llorca J. Insulin resistance in rheumatoid arthritis: the impact of the anti-TNF-alpha therapy. Ann N Y Acad Sci. 2010 Apr;1193:153-9. doi: 10.1111/j.1749-6632.2009.05287.x. Review. PubMed PMID: 20398022.
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  185. González-Gay MA, González-Juanatey C. Rheumatoid arthritis: Obesity impairs efficacy of anti-TNF therapy in patients with RA. Nat Rev Rheumatol. 2012 Nov;8(11):641-2. doi: 10.1038/nrrheum.2012.158. Epub 2012 Sep 25. PubMed PMID: 23007743.
  186. González-Gay MA, González-Vela C, González-Juanatey C. Psoriasis: a skin disease associated with increased cardiovascular risk. Actas Dermosifiliogr. 2012 Sep;103(7):595-8. Epub 2012 Mar 31. Review. English, Spanish. PubMed PMID: 22465257.
  187. Gonzalez-Gay MA, Llorca J, Garcia-Unzueta MT, Gonzalez-Juanatey C, De Matias JM, Martin J, Redelinghuys M, Woodiwiss AJ, Norton GR, Dessein PH. High-grade inflammation, circulating adiponectin concentrations and cardiovascular risk factors in severe rheumatoid arthritis. Clin Exp Rheumatol. 2008 Jul-Aug;26(4):596-603. PubMed PMID: 18799090.
  188. Gonzalez-Gay MA, Llorca J, Palomino-Morales R, Gomez-Acebo I, Gonzalez-Juanatey C, Martin J. Influence of nitric oxide synthase gene polymorphisms on the risk of cardiovascular events in rheumatoid arthritis. Clin Exp Rheumatol. 2009 Jan-Feb;27(1):116-9. PubMed PMID: 19327239.
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  190. Gonzalez-Gay MA, Oliver J, Sanchez E, Garcia-Porrua C, Paco L, Lopez-Nevot MA, Ollier WE, Martin J. Association of a functional inducible nitric oxide synthase promoter variant with susceptibility to biopsy-proven giant cell arteritis. J Rheumatol. 2005 Nov;32(11):2178-82. PubMed PMID: 16265698.
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  192. Gonzalez-Gay MA, Rubiera G, Piñeiro A, Garcia-Porrua C, Pego-Reigosa R, Gonzalez-Juanatey C, Sanchez-Andrade A, Llorca J. Ischemic heart disease in patients from Northwest Spain with biopsy proven giant cell arteritis. A population based study. J Rheumatol. 2005 Mar;32(3):502-6. PubMed PMID: 15742443.
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  195. Gonzalez-Gay MA, Vazquez-Rodriguez TR, Garcia-Unzueta MT, Berja A, Miranda-Filloy JA, de Matias JM, Gonzalez-Juanatey C, Llorca J. Visfatin is not associated with inflammation or metabolic syndrome in patients with severe rheumatoid arthritis undergoing anti-TNF-alpha therapy. Clin Exp Rheumatol. 2010  Jan-Feb;28(1):56-62. PubMed PMID: 20346239.
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  198. Gonzalez-Gay MA. Glucocorticoid-related cardiovascular and cerebrovascular events in rheumatic diseases: myth or reality? Arthritis Rheum. 2007 Mar 15;57(2):191-2. PubMed PMID: 17330291.
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