Relevant Publications

1: Bayley R, Kite KA, McGettrick HM, Smith JP, Kitas GD, Buckley CD, Young SP. The autoimmune-associated genetic variant PTPN22 R620W enhances neutrophil activation and function in patients with rheumatoid arthritis and healthy individuals. Ann Rheum Dis. 2014 Mar 24. doi: 10.1136/annrheumdis-2013-204796. [Epub ahead of print] PubMed PMID: 24665115.

2: Saratzis A, Bown MJ, Wild B, Nightingale P, Smith J, Johnson C, Melas N, Kitas GD. Association between seven single nucleotide polymorphisms involved in inflammation and proteolysis and abdominal aortic aneurysm. J Vasc Surg. 2014 Mar 7. pii: S0741-5214(14)00170-0. doi: 10.1016/j.jvs.2013.11.099. [Epub ahead of print] PubMed PMID: 24613192.

3: Semb AG, Rollefstad S, van Riel P, Kitas GD, Matteson EL, Gabriel SE. Cardiovascular disease assessment in rheumatoid arthritis: a guide to translating knowledge of cardiovascular risk into clinical practice. Ann Rheum Dis. 2014 Mar 7. doi: 10.1136/annrheumdis-2013-204792. [Epub ahead of print] PubMed PMID: 24608403.

4: Mavrogeni S, Sfikakis PP, Karabela G, Stavropoulos E, Kolovou G, Kitas GD. “All roads lead to Rome” ventricular tachycardia due to right ventricle involvement in autoimmune and non-autoimmune disease. Int J Cardiol. 2014 Feb 22. pii: S0167-5273(14)00372-6. doi: 10.1016/j.ijcard.2014.02.019. [Epub ahead of print] PubMed PMID: 24598233.

5: Sandoo A, Kitas GD, Carmichael AR. Endothelial Dysfunction as a Determinant of Trastuzumab-mediated Cardiotoxicity in Patients with Breast Cancer. Anticancer Res. 2014 Mar;34(3):1147-51. PubMed PMID: 24596352.

6: Mavrogeni S, Sfikakis P, Dimitroulas T, Kolovou G, Kitas GD. Edema and fibrosis imaging by cardiovascular magnetic resonance: How can the experience of Cardiology be best utilized in rheumatological practice? Semin Arthritis Rheum. 2014 Jan 23. pii: S0049-0172(14)00006-7. doi: 10.1016/j.semarthrit.2014.01.005. [Epub ahead of print] Review. PubMed PMID: 24582213.

7: Tam LS, Kitas GD, González-Gay MA. Can suppression of inflammation by anti-TNF prevent progression of subclinical atherosclerosis in inflammatory arthritis? Rheumatology (Oxford). 2014 Feb 28. [Epub ahead of print] PubMed PMID: 24501245.

8: Mavrogeni S, Dimitroulas T, Buccareli-Ducci C, Ardoin S, Sfikakis PP, Kolovou G, Kitas GD. Rheumatoid arthritis: an autoimmune disease with female preponderance and cardiovascular risk equivalent to Diabetes Mellitus: Role of Cardiovascular Magnetic Resonance. Inflamm Allergy Drug Targets. 2014 Jan 31. [Epub ahead of print] PubMed PMID: 24479835.

9: Mavrogeni S, Kouranos V, Sfikakis PP, Bratis K, Kitas GD, Manali E, Perros E, Vlasis K, Rapti A, Koulouris N, van Wijk K, Hautemann D, Reiber JH, Kolovou G, Tzelepis GE, Gialafos E. Myocardial stress perfusion-fibrosis imaging pattern in sarcoidosis, assessed by cardiovascular magnetic resonance imaging. Int J Cardiol. 2014 Mar 15;172(2):501-3. doi: 10.1016/j.ijcard.2014.01.006. Epub 2014 Jan 16. PubMed PMID: 24476697.

10: Dimitroulas T, Sandoo A, Smith JP, Kitas GD. Asymmetric dimethylarginine is not associated with subendocardial viability ratio in Rheumatoid Arthritis. Int J Cardiol. 2014 Mar 1;172(1):285-6. doi: 10.1016/j.ijcard.2013.12.235. Epub 2014 Jan 10. PubMed PMID: 24447745.

11: Arts EE, Popa C, Den Broeder AA, Semb AG, Toms T, Kitas GD, van Riel PL, Fransen J. Performance of four current risk algorithms in predicting cardiovascular events in patients with early rheumatoid arthritis. Ann Rheum Dis. 2014 Jan 3. doi: 10.1136/annrheumdis-2013-204024. [Epub ahead of print] PubMed PMID: 24389293.

12: Saratzis A, Saedon M, Melas N, Kitas GD, Mahmood A. Obesity as an Independent Predictor of Outcome after Endovascular Abdominal Aortic Aneurysm Repair. Ann Vasc Surg. 2013 Dec 27. pii: S0890-5096(13)00481-0. doi: 10.1016/j.avsg.2013.07.008. [Epub ahead of print] PubMed PMID: 24378248.

13: Mavrogeni S, Sfikakis PP, Karabela G, Stavropoulos E, Spiliotis G, Gialafos E, Panopoulos S, Bournia V, Manolopoulou D, Kolovou G, Kitas G. Cardiovascular magnetic resonance imaging in asymptomatic patients with connective tissue disease and recent onset left bundle branch block. Int J Cardiol. 2014 Jan 15;171(1):82-7. doi: 10.1016/j.ijcard.2013.11.059. Epub 2013 Dec 4. PubMed PMID: 24331867.

14: Yarwood A, Viatte S, Plant D, Morgan AW, Isaacs J, Wilson AG, Hyrich K, Eyre S, Barton A; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS). Testing the role of vitamin D in response to antitumour necrosis factor α therapy in a UK cohort: a Mendelian randomisation approach. Ann Rheum Dis. 2013 Dec 9. doi: 10.1136/annrheumdis-2013-204443. [Epub ahead of print] PubMed PMID: 24323394.

15: Sandoo A, Chanchlani N, Hodson J, Smith JP, Douglas KM, Kitas GD. Classical cardiovascular disease risk factors associate with vascular function and morphology in rheumatoid arthritis: a six-year prospective study. Arthritis Res Ther. 2013;15(6):R203. PubMed PMID: 24289091.

16: Protogerou AD, Panagiotakos DB, Zampeli E, Argyris AA, Arida K, Konstantonis GD, Pitsavos C, Kitas GD, Sfikakis PP. Arterial hypertension assessed “out-of-office” in a contemporary cohort of rheumatoid arthritis patients free of cardiovascular disease is characterized by high prevalence, low awareness, poor control and increased vascular damage-associated “white coat” phenomenon. Arthritis Res Ther. 2013 Oct 2;15(5):R142. doi: 10.1186/ar4324. PubMed PMID: 24286134.

17: Sattar N, Kitas GD. Rheumatoid arthritis: Testing the inflammation-insulin resistance link in clinical trials. Nat Rev Rheumatol. 2013 Dec;9(12):702-3. doi: 10.1038/nrrheum.2013.178. Epub 2013 Nov 19. PubMed PMID: 24247367.

18: Saratzis A, Bown M, Wild B, Sayers RD, Nightingale P, Smith J, Johnson C, Kitas G. C-reactive protein polymorphism rs3091244 is associated with abdominal aortic aneurysm. J Vasc Surg. 2013 Oct 14. pii: S0741-5214(13)01456-0. doi: 10.1016/j.jvs.2013.07.105. [Epub ahead of print] PubMed PMID: 24135623.

19: Mavrogeni S, Sfikakis PP, Gialafos E, Bratis K, Karabela G, Stavropoulos E, Spiliotis G, Sfendouraki E, Panopoulos S, Bournia V, Kolovou G, Kitas GD. Cardiac tissue characterization and the diagnostic value of cardiovascular magnetic resonance in systemic connective tissue diseases. Arthritis Care Res (Hoboken). 2014 Jan;66(1):104-12. doi: 10.1002/acr.22181. PubMed PMID: 24106233.

20: Panoulas VF, Toms TE, Douglas KM, Sandoo A, Metsios GS, Stavropoulos-Kalinoglou A, Kitas GD. Prolonged QTc interval predicts all-cause mortality in patients with rheumatoid arthritis: an association driven by high inflammatory burden. Rheumatology (Oxford). 2014 Jan;53(1):131-7. doi: 10.1093/rheumatology/ket338. Epub 2013 Oct 3. PubMed PMID: 24097136.

21: Cutolo M, Kitas GD, van Riel PL. Burden of disease in treated rheumatoid arthritis patients: going beyond the joint. Semin Arthritis Rheum. 2014 Feb;43(4):479-88. doi: 10.1016/j.semarthrit.2013.08.004. Epub 2013 Sep 27. PubMed PMID: 24080116.

22: Sandoo A, Hodson J, Douglas KM, Smith JP, Kitas GD. The association between functional and morphological assessments of endothelial function in patients with rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther. 2013;15(5):R107. PubMed PMID: 24010810.

23: Metsios GS, Stavropoulos-Kalinoglou A, Veldhuijzen van Zanten JJ, Nightingale P, Sandoo A, Dimitroulas T, Kitas GD, Koutedakis Y. Individualised exercise improves endothelial function in patients with rheumatoid arthritis. Ann Rheum Dis. 2014 Apr 1;73(4):748-51. doi: 10.1136/annrheumdis-2013-203291. Epub 2013 Jul 31. PubMed PMID: 23904472.

24: Bluett J, Ibrahim I, Plant D, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD; BRAGGSS, Barton A. Association of a complement receptor 1 gene variant with baseline erythrocyte sedimentation rate levels in patients starting anti-TNF therapy in a UK rheumatoid arthritis cohort: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort. Pharmacogenomics J. 2014 Apr;14(2):171-5. doi: 10.1038/tpj.2013.26. Epub 2013 Jul 16. PubMed PMID: 23856853; PubMed Central PMCID: PMC3965567.

25: Mavrogeni S, Dimitroulas T, Sfikakis PP, Kitas GD. Heart involvement in rheumatoid arthritis: multimodality imaging and the emerging role of cardiac magnetic resonance. Semin Arthritis Rheum. 2013 Dec;43(3):314-24. doi: 10.1016/j.semarthrit.2013.05.001. Epub 2013 Jun 17. PubMed PMID: 23786873.

26: Young SP, Kapoor SR, Viant MR, Byrne JJ, Filer A, Buckley CD, Kitas GD, Raza K. The impact of inflammation on metabolomic profiles in patients with arthritis. Arthritis Rheum. 2013 Aug;65(8):2015-23. doi: 10.1002/art.38021. PubMed PMID: 23740368; PubMed Central PMCID: PMC3840700.

27: Saratzis A, Sarafidis P, Melas N, Saratzis N, Kitas G. Impaired renal function is associated with mortality and morbidity after endovascular abdominal aortic aneurysm repair. J Vasc Surg. 2013 Oct;58(4):879-85. doi: 10.1016/j.jvs.2013.03.036. Epub 2013 May 14. PubMed PMID: 23683383.

28: Dimitroulas T, Douglas KM, Panoulas VF, Toms T, Smith JP, Treharne GJ, Nightingale P, Hodson J, Kitas GD. Derangement of hemostasis in rheumatoid arthritis: association with demographic, inflammatory and metabolic factors. Clin Rheumatol. 2013 Sep;32(9):1357-64. doi: 10.1007/s10067-013-2283-6. Epub 2013 May 15. PubMed PMID: 23673438.

29: Mavrogeni S, Sfikakis PP, Gialafos E, Karabela G, Stavropoulos E, Sfendouraki E, Panopoulos S, Kolovou G, Kitas GD. Diffuse, subendocardial vasculitis. A new entity identified by cardiovascular magnetic resonance and its clinical implications. Int J Cardiol. 2013 Oct 3;168(3):2971-2. doi: 10.1016/j.ijcard.2013.04.116. Epub 2013 May 4. PubMed PMID: 23647593.

30: Bamias G, Stamatelopoulos K, Zampeli E, Protogerou A, Sigala F, Papamichael C, Christopoulos P, Kitas GD, Sfikakis PP. Circulating levels of TNF-like cytokine 1A correlate with the progression of atheromatous lesions in patients with rheumatoid arthritis. Clin Immunol. 2013 May;147(2):144-50. doi: 10.1016/j.clim.2013.03.002. Epub 2013 Mar 26. PubMed PMID: 23598291.

31: Dimitroulas T, Giannakoulas G, Karvounis H, Garyfallos A, Settas L, Kitas GD. Micro- and macrovascular treatment targets in scleroderma heart disease. Curr Pharm Des. 2014;20(4):536-44. PubMed PMID: 23565639.

32: Gasparyan AY, Ayvazyan L, Pretorius E, Kitas GD. Platelets in rheumatic diseases: friend or foe? Curr Pharm Des. 2014;20(4):552-66. PubMed PMID: 23565634.

33: Dimitroulas T, Sandoo A, Veldhuijzen van Zanten JJ, Smith JP, Hodson J, Metsios GS, Stavropoulos-Kalinoglou A, Kitas GD. Predictors of asymmetric dimethylarginine levels in patients with rheumatoid arthritis: the role of insulin resistance. Scand J Rheumatol. 2013;42(3):176-81. doi: 10.3109/03009742.2012.747627. Epub 2013 Jan 14. PubMed PMID: 23311682.

34: Dimitroulas T, Sandoo A, Kitas GD. Asymmetric dimethylarginine as a surrogate marker of endothelial dysfunction and cardiovascular risk in patients with systemic rheumatic diseases. Int J Mol Sci. 2012 Sep 26;13(10):12315-35. doi: 10.3390/ijms131012315. PubMed PMID: 23202900; PubMed Central PMCID: PMC3497274.

35: Sandoo A, Protogerou AD, Hodson J, Smith JP, Zampeli E, Sfikakis PP, Kitas GD. The role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study. Arthritis Res Ther. 2012 Nov 28;14(6):R258. [Epub ahead of print] PubMed PMID: 23190682; PubMed Central PMCID: PMC3674609.

36: Toutouzas K, Sfikakis PP, Karanasos A, Aggeli C, Felekos I, Kitas G, Zampeli E, Protogerou A, Stefanadis C. Myocardial ischaemia without obstructive coronary artery disease in rheumatoid arthritis: hypothesis-generating insights from a cross-sectional study. Rheumatology (Oxford). 2013 Jan;52(1):76-80. doi: 10.1093/rheumatology/kes349. Epub 2012 Nov 26. PubMed PMID: 23185038.

37: Stavropoulos-Kalinoglou A, Metsios GS, Veldhuijzen van Zanten JJ, Nightingale P, Kitas GD, Koutedakis Y. Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis. Ann Rheum Dis. 2013 Nov 1;72(11):1819-25. doi: 10.1136/annrheumdis-2012-202075. Epub 2012 Nov 15. PubMed PMID: 23155222.

38: Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, Trynka G, Franke L, Westra HJ, Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, Hunt SE, Langford C, Symmons D; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Wellcome Trust Case Control Consortium, Concannon P, Onengut-Gumuscu S, Rich SS, Deloukas P, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlsetig L, Martin J, Rantapää-Dahlqvist S, Plenge RM, Raychaudhuri S, Klareskog L, Gregersen PK, Worthington J. High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. Nat Genet. 2012 Dec;44(12):1336-40. doi: 10.1038/ng.2462. Epub 2012 Nov 11. PubMed PMID: 23143596; PubMed Central PMCID: PMC3605761.

39: John H, Hale ED, Treharne GJ, Kitas GD, Carroll D. A randomized controlled trial of a cognitive behavioural patient education intervention vs a traditional information leaflet to address the cardiovascular aspects of rheumatoid disease. Rheumatology (Oxford). 2013 Jan;52(1):81-90. doi: 10.1093/rheumatology/kes237. Epub 2012 Sep 1. PubMed PMID: 22942402.

40: Mavrogeni S, Dimitroulas T, Chatziioannou SN, Kitas G. The role of multimodality imaging in the evaluation of Takayasu arteritis. Semin Arthritis Rheum. 2013 Feb;42(4):401-12. doi: 10.1016/j.semarthrit.2012.07.005. Epub 2012 Aug 22. Review. PubMed PMID: 22920236.

41: John H, Kitas G. Inflammatory arthritis as a novel risk factor for cardiovascular disease. Eur J Intern Med. 2012 Oct;23(7):575-9. doi: 10.1016/j.ejim.2012.06.016. Epub 2012 Jul 28. Review. PubMed PMID: 22841864.

42: Sandoo A, van Zanten JJ, Toms TE, Carroll D, Kitas GD. Anti-TNFα therapy transiently improves high density lipoprotein cholesterol levels and microvascular endothelial function in patients with rheumatoid arthritis: a pilot study. BMC Musculoskelet Disord. 2012 Jul 23;13:127. doi: 10.1186/1471-2474-13-127. PubMed PMID: 22824166; PubMed Central PMCID: PMC3502606.

43: Sandoo A, Dimitroulas T, Toms TE, Hodson J, Veldhuijzen van Zanten JJ, Smith JP, Kitas GD. Clinical remission following treatment with tumour necrosis factor-alpha antagonists is not accompanied by changes in asymmetric dimethylarginine in patients with rheumatoid arthritis. Clin Biochem. 2012 Nov;45(16-17):1399-403. doi: 10.1016/j.clinbiochem.2012.07.092. Epub 2012 Jul 20. PubMed PMID: 22820438.

44: Protogerou AD, Kitas GD, Sfikakis PP. Importance of standardized methodology to comparisons between studies of rheumatoid arthritis and cardiovascular disease: comment on the article by Giles et al. Arthritis Rheum. 2012 Oct;64(10):3487-8; author reply 3488. doi: 10.1002/art.34612. PubMed PMID: 22777506.

45: Stavropoulos-Kalinoglou A, Metsios GS, Panoulas VF, Nightingale P, Koutedakis Y, Kitas GD. Anti-tumour necrosis factor alpha therapy improves insulin sensitivity in normal-weight but not in obese patients with rheumatoid arthritis. Arthritis Res Ther. 2012 Jul 5;14(4):R160. [Epub ahead of print] PubMed PMID: 22765047; PubMed Central PMCID: PMC3580552.

46: Protogerou A, Zampeli E, Tentolouris N, Makrilakis K, Kitas G, Sfikakis PP. Subclinical femoral atheromatosis in rheumatoid arthritis: comparable prevalence to diabetes mellitus in a case-control study. Ann Rheum Dis. 2012 Sep;71(9):1534-6. doi: 10.1136/annrheumdis-2011-201278. Epub 2012 Jul 4. PubMed PMID: 22764043.

47: Paschalis V, Nikolaidis MG, Jamurtas AZ, Owolabi EO, Kitas GD, Wyon MA, Koutedakis Y. Dance as an eccentric form of exercise: practical implications. Med Probl Perform Art. 2012 Jun;27(2):102-6. Review. PubMed PMID: 22739823.

48: Mavrogeni S, Dimitroulas T, Kitas GD. Multimodality imaging and the emerging role of cardiac magnetic resonance in autoimmune myocarditis. Autoimmun Rev. 2012 Dec;12(2):305-12. doi: 10.1016/j.autrev.2012.05.005. Epub 2012 May 19. Review. PubMed PMID: 22617620.

49: Sandoo A, Kitas GD, Carroll D, Veldhuijzen van Zanten JJ. The role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study. Arthritis Res Ther. 2012 May 17;14(3):R117. doi: 10.1186/ar3847. PubMed PMID: 22594788; PubMed Central PMCID: PMC3446498.

50: Saratzis A, Melas N, Hunter JP, Dixon H, Nightingale P, Kiskinis D, Saratzis N, Kitas GD. Anemia is associated with mortality following endovascular repair of abdominal aortic aneurysm. Vasc Endovascular Surg. 2012 Apr;46(3):223-8. doi: 10.1177/1538574412442251. Epub 2012 Apr 9. PubMed PMID: 22492108.

51: Fisher BA, Plant D, Lundberg K, Charles P, Barton A, Venables PJ; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS). Heterogeneity of anticitrullinated peptide antibodies and response to anti-tumor necrosis factor agents in rheumatoid arthritis. J Rheumatol. 2012 May;39(5):929-32. doi: 10.3899/jrheum.111315. Epub 2012 Apr 1. PubMed PMID: 22467927.

52: Dimitroulas T, Douglas KM, Smith J, Panoulas VF, Kitas GD. Lack of association between polymorphisms of thrombogenic genes and disease susceptibility in rheumatoid arthritis. Rheumatol Int. 2013 Sep;33(9):2429-32. doi: 10.1007/s00296-012-2392-6. Epub 2012 Mar 31. PubMed PMID: 22466403.

53: Sandoo A, Dimitroulas T, Veldhuijzen van Zanten JJ, Smith JP, Metsios GS, Nightingale P, Stavropoulos-Kalinoglou A, Kitas GD. Lack of association between asymmetric dimethylarginine and in vivo microvascular and macrovascular endothelial function in patients with rheumatoid arthritis. Clin Exp Rheumatol. 2012 May-Jun;30(3):388-96. Epub 2012 Jun 26. PubMed PMID: 22410121.

54: Dimitroulas T, Giannakoulas G, Karvounis H, Garyfallos A, Settas L, Kitas G. B-type natriuretic peptide in rheumatic diseases: a cardiac biomarker or a sophisticated acute phase reactant? Autoimmun Rev. 2012 Oct;11(12):837-43. doi: 10.1016/j.autrev.2012.02.018. Epub 2012 Feb 28. Review. PubMed PMID: 22401930.

55: Zampeli E, Protogerou A, Stamatelopoulos K, Fragiadaki K, Katsiari CG, Kyrkou K, Papamichael CM, Mavrikakis M, Nightingale P, Kitas GD, Sfikakis PP. Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study. Arthritis Res Ther. 2012 Mar 5;14(2):R44. doi: 10.1186/ar3757. PubMed PMID: 22390577; PubMed Central PMCID: PMC3446411.

56: Gasparyan AY, Ayvazyan L, Cocco G, Kitas GD. Adverse cardiovascular effects of antirheumatic drugs: implications for clinical practice and research. Curr Pharm Des. 2012;18(11):1543-55. Review. PubMed PMID: 22364138.

57: Rontoyanni VG, Sfikakis PP, Kitas GD, Protogerou AD. Marine n-3 fatty acids for cardiovascular risk reduction and disease control in rheumatoid arthritis: “kill two birds with one stone”? Curr Pharm Des. 2012;18(11):1531-42. Review. PubMed PMID: 22364137.

58: Dimitroulas T, Giannakoulas G, Karvounis H, Settas L, Kitas GD. Systemic sclerosis-related pulmonary hypertension: unique characteristics and future treatment targets. Curr Pharm Des. 2012;18(11):1457-64. Review. PubMed PMID: 22364130.

59: Dimitroulas T, Mavrogeni S, Kitas GD. Imaging modalities for the diagnosis of pulmonary hypertension in systemic sclerosis. Nat Rev Rheumatol. 2012 Feb 7;8(4):203-13. doi: 10.1038/nrrheum.2012.2. Review. PubMed PMID: 22310183.

60: Toms TE, Smith JP, Panoulas VF, Blackmore H, Douglas KM, Kitas GD. Apolipoprotein E gene polymorphisms are strong predictors of inflammation and dyslipidemia in rheumatoid arthritis. J Rheumatol. 2012 Feb;39(2):218-25. doi: 10.3899/jrheum.110683. Epub 2011 Dec 15. PubMed PMID: 22174202. 61: Griffiths HR, Dunston CR, Bennett SJ, Grant MM, Phillips DC, Kitas GD. Free radicals and redox signalling in T-cells during chronic inflammation and ageing. Biochem Soc Trans. 2011 Oct;39(5):1273-8. doi: 10.1042/BST0391273. PubMed PMID: 21936801.

62: Sandoo A, Veldhuijzen van Zanten JJ, Metsios GS, Carroll D, Kitas GD. Vascular function and morphology in rheumatoid arthritis: a systematic review. Rheumatology (Oxford). 2011 Nov;50(11):2125-39. doi: 10.1093/rheumatology/ker275. Epub 2011 Sep 16. Review. PubMed PMID: 21926155.

63: Nevill AM, Stavropoulos-Kalinoglou A, Metsios GS, Koutedakis Y, Holder RL, Kitas GD, Mohammed MA. Inverted BMI rather than BMI is a better proxy for percentage of body fat. Ann Hum Biol. 2011 Nov;38(6):681-4. doi: 10.3109/03014460.2011.606832. Epub 2011 Aug 17. PubMed PMID: 21846303.

64: John H, Carroll D, Kitas GD. Cardiovascular education for people with rheumatoid arthritis: what can existing patient education programmes teach us? Rheumatology (Oxford). 2011 Oct;50(10):1751-9. doi: 10.1093/rheumatology/ker191. Epub 2011 Jul 9. Review. PubMed PMID: 21743087.

65: Metsios GS, Stavropoulos-Kalinoglou A, Treharne GJ, Nevill AM, Sandoo A, Panoulas VF, Toms TE, Koutedakis Y, Kitas GD. Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis. Arthritis Res Ther. 2011 Jun 29;13(3):R108. doi: 10.1186/ar3390. PubMed PMID: 21714856; PubMed Central PMCID: PMC3218923.

66: Sandoo A, Carroll D, Metsios GS, Kitas GD, Veldhuijzen van Zanten JJ. The association between microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther. 2011 Jun 21;13(3):R99. doi: 10.1186/ar3374. PubMed PMID: 21693023; PubMed Central PMCID: PMC3218914.

67: Toms TE, Panoulas VF, Kitas GD. Dyslipidaemia in rheumatological autoimmune diseases. Open Cardiovasc Med J. 2011;5:64-75. doi: 10.2174/1874192401105010064. Epub 2011 Feb 24. PubMed PMID: 21660202; PubMed Central PMCID: PMC3109701.

68: John H, Hale ED, Treharne GJ, Korontzis K, Obrenovic K, Carroll D, Kitas GD. Patient evaluation of a novel patient education leaflet about heart disease risk among people with rheumatoid arthritis. Musculoskeletal Care. 2011 Dec;9(4):194-9. doi: 10.1002/msc.207. Epub 2011 May 6. PubMed PMID: 21557439.

69: Sandoo A, Panoulas VF, Toms TE, Smith JP, Stavropoulos-Kalinoglou A, Metsios GS, Gasparyan AY, Carroll D, Veldhuijzen van Zanten JJ, Kitas GD. Anti-TNFα therapy may lead to blood pressure reductions through improved endothelium-dependent microvascular function in patients with rheumatoid arthritis. J Hum Hypertens. 2011 Nov;25(11):699-702. doi: 10.1038/jhh.2011.36. Epub 2011 Apr 28. PubMed PMID: 21525886.

70: John H, Toms TE, Kitas GD. Rheumatoid arthritis: is it a coronary heart disease equivalent? Curr Opin Cardiol. 2011 Jul;26(4):327-33. doi: 10.1097/HCO.0b013e32834703b5. Review. PubMed PMID: 21499088.

71: Nurmohamed MT, Kitas G. Cardiovascular risk in rheumatoid arthritis and diabetes: how does it compare and when does it start? Ann Rheum Dis. 2011 Jun;70(6):881-3. doi: 10.1136/ard.2010.145839. Epub 2011 Mar 30. PubMed PMID: 21450751.

72: Toms TE, Panoulas VF, Smith JP, Douglas KM, Metsios GS, Stavropoulos-Kalinoglou A, Kitas GD. Rheumatoid arthritis susceptibility genes associate with lipid levels in patients with rheumatoid arthritis. Ann Rheum Dis. 2011 Jun;70(6):1025-32. doi: 10.1136/ard.2010.144634. Epub 2011 Mar 11. PubMed PMID: 21398331.

73: Sandoo A, van Zanten JJ, Metsios GS, Carroll D, Kitas GD. The endothelium and its role in regulating vascular tone. Open Cardiovasc Med J. 2010 Dec 23;4:302-12. doi: 10.2174/1874192401004010302. PubMed PMID: 21339899; PubMed Central PMCID: PMC3040999.

74: Shanker J, Gasparyan AY, Kitas GD, Kakkar VV. Platelet function and antiplatelet therapy in cardiovascular disease: implications of genetic polymorphisms. Curr Vasc Pharmacol. 2011 Jul 1;9(4):479-89. Review. PubMed PMID: 21314637.

75: Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD. Mean platelet volume: a link between thrombosis and inflammation? Curr Pharm Des. 2011;17(1):47-58. Review. PubMed PMID: 21247392.

76: Dimitroulas T, Giannakoulas G, Karvounis H, Settas L, Kitas GD. Biomarkers in systemic sclerosis-related pulmonary arterial hypertension. Curr Vasc Pharmacol. 2011 Mar;9(2):213-9. Review. PubMed PMID: 21143174.

77: Verstappen SM, McCoy MJ, Roberts C, Dale NE, Hassell AB, Symmons DP; Steroids In Very Early Arthritis Investigators. Disease activity, smoking, and reproductive-related predictors of poor prognosis in patients with very early inflammatory polyarthritis. J Rheumatol. 2011 Mar;38(3):429-33. doi: 10.3899/jrheum.100756. Epub 2010 Dec 1. PubMed PMID: 21123320.

78: Daoussis D, Kitas GD. Uric acid and cardiovascular risk in rheumatoid arthritis. Rheumatology (Oxford). 2011 Aug;50(8):1354-5. doi: 10.1093/rheumatology/keq388. Epub 2010 Nov 28. PubMed PMID: 21115462.

79: Kitas GD, Gabriel SE. Cardiovascular disease in rheumatoid arthritis: state of the art and future perspectives. Ann Rheum Dis. 2011 Jan;70(1):8-14. doi: 10.1136/ard.2010.142133. Epub 2010 Nov 24. Review. Erratum in: Ann Rheum Dis. 2011 Aug;70(8):1520. PubMed PMID: 21109513.

80: Toms TE, Panoulas VF, Douglas KM, Nightingale P, Smith JP, Griffiths H, Sattar N, Symmons DP, Kitas GD. Are lipid ratios less susceptible to change with systemic inflammation than individual lipid components in patients with rheumatoid arthritis? Angiology. 2011 Feb;62(2):167-75. doi: 10.1177/0003319710373749. Epub 2010 Aug 3. PubMed PMID: 20682616.

81: Lunt M, Watson KD, Dixon WG; British Society for Rheumatology Biologics Register Control Centre Consortium, Symmons DP, Hyrich KL; British Society for Rheumatology Biologics Register. No evidence of association between anti-tumor necrosis factor treatment and mortality in patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register. Arthritis Rheum. 2010 Nov;62(11):3145-53. doi: 10.1002/art.27660. PubMed PMID: 20662063; PubMed Central PMCID: PMC3061010.

82: Summers GD, Metsios GS, Stavropoulos-Kalinoglou A, Kitas GD. Rheumatoid cachexia and cardiovascular disease. Nat Rev Rheumatol. 2010 Aug;6(8):445-51. doi: 10.1038/nrrheum.2010.105. Epub 2010 Jul 20. Review. PubMed PMID: 20647995.

83: John H, Hale ED, Bennett P, Treharne GJ, Carroll D, Kitas GD. Translating patient education theory into practice: developing material to address the cardiovascular education needs of people with rheumatoid arthritis. Patient Educ Couns. 2011 Jul;84(1):123-7. doi: 10.1016/j.pec.2010.06.023. Epub 2010 Jul 17. PubMed PMID: 20638217; PubMed Central PMCID: PMC3123736.

84: Saratzis A, Abbas AA, Kiskinis D, Melas N, Saratzis N, Kitas GD. Abdominal aortic aneurysm: a review of the genetic basis. Angiology. 2011 Jan;62(1):18-32. doi: 10.1177/0003319710373092. Epub 2010 Jun 21. Review. PubMed PMID: 20566578.

85: Stamatelopoulos KS, Kitas GD, Papamichael CM, Kyrkou K, Zampeli E, Fragiadaki K, Panoulas VF, Mavrikakis M, Sfikakis PP. Subclinical peripheral arterial disease in rheumatoid arthritis. Atherosclerosis. 2010 Sep;212(1):305-9. doi: 10.1016/j.atherosclerosis.2010.05.007. Epub 2010 May 12. PubMed PMID: 20553683.

86: Daoussis D, Panoulas VF, John H, Toms TE, Antonopoulos I, Treharne G, Nightingale P, Douglas KM, Kitas GD. Microalbuminuria in rheumatoid arthritis in the post penicillamine/gold era: association with hypertension, but not therapy or inflammation. Clin Rheumatol. 2011 Apr;30(4):477-84. doi: 10.1007/s10067-010-1446-y. Epub 2010 Apr 16. PubMed PMID: 20396921.

87: Gasparyan AY, Stavropoulos-Kalinoglou A, Mikhailidis DP, Douglas KM, Kitas GD. Platelet function in rheumatoid arthritis: arthritic and cardiovascular implications. Rheumatol Int. 2011 Feb;31(2):153-64. doi: 10.1007/s00296-010-1446-x. Review. PubMed PMID: 20390282.

88: Metsios GS, Stavropoulos-Kalinoglou A, Sandoo A, van Zanten JJ, Toms TE, John H, Kitas GD. Vascular function and inflammation in rheumatoid arthritis: the role of physical activity. Open Cardiovasc Med J. 2010 Feb 23;4:89-96. doi: 10.2174/1874192401004020089. PubMed PMID: 20361002; PubMed Central PMCID: PMC2847820.

89: Metsios GS, Stavropoulos-Kalinoglou A, Panoulas VF, Sandoo A, Toms TE, Nevill AM, Koutedakis Y, Kitas GD. Rheumatoid cachexia and cardiovascular disease. Clin Exp Rheumatol. 2009 Nov-Dec;27(6):985-8. PubMed PMID: 20149317.

90: Gasparyan AY, Sandoo A, Stavropoulos-Kalinoglou A, Kitas GD. Mean platelet volume in patients with rheumatoid arthritis: the effect of anti-TNF-α therapy. Rheumatol Int. 2010 Jun;30(8):1125-9. doi: 10.1007/s00296-009-1345-1. Epub 2010 Jan 12. PubMed PMID: 20066426.

91: Peters MJ, Nurmohamed MT, Kitas GD, Sattar N. Statin treatment of rheumatoid arthritis: comment on the editorial by Ridker and Solomon. Arthritis Rheum. 2010 Jan;62(1):302-3. doi: 10.1002/art.25054. PubMed PMID: 20039426.

92: Hassan B, Maxwell JR, Hyrich KL; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, Barton A, Worthington J, Isaacs JD, Morgan AW, Wilson AG. Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis. Rheumatology (Oxford). 2010 Jan;49(1):43-7. doi: 10.1093/rheumatology/kep372. Epub 2009 Nov 19. PubMed PMID: 19926672.

93: Gasparyan AY, Stavropoulos-Kalinoglou A, Toms TE, Douglas KM, Kitas GD. Association of mean platelet volume with hypertension in rheumatoid arthritis. Inflamm Allergy Drug Targets. 2010 Mar;9(1):45-50. PubMed PMID: 19906007.

94: Raychaudhuri S, Thomson BP, Remmers EF, Eyre S, Hinks A, Guiducci C, Catanese JJ, Xie G, Stahl EA, Chen R, Alfredsson L, Amos CI, Ardlie KG; BIRAC Consortium, Barton A, Bowes J, Burtt NP, Chang M, Coblyn J, Costenbader KH, Criswell LA, Crusius JB, Cui J, De Jager PL, Ding B, Emery P, Flynn E, Harrison P, Hocking LJ, Huizinga TW, Kastner DL, Ke X, Kurreeman FA, Lee AT, Liu X, Li Y, Martin P, Morgan AW, Padyukov L, Reid DM, Seielstad M, Seldin MF, Shadick NA, Steer S, Tak PP, Thomson W, van der Helm-van Mil AH, van der Horst-Bruinsma IE, Weinblatt ME, Wilson AG, Wolbink GJ, Wordsworth P; YEAR Consortium, Altshuler D, Karlson EW, Toes RE, de Vries N, Begovich AB, Siminovitch KA, Worthington J, Klareskog L, Gregersen PK, Daly MJ, Plenge RM. Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk. Nat Genet. 2009 Dec;41(12):1313-8. doi: 10.1038/ng.479. Epub 2009 Nov 8. PubMed PMID: 19898481; PubMed Central PMCID: PMC3142887.

95: Stavropoulos-Kalinoglou A, Metsios GS, Smith JP, Panoulas VF, Douglas KM, Jamurtas AZ, Koutedakis Y, Kitas GD. What predicts obesity in patients with rheumatoid arthritis? An investigation of the interactions between lifestyle and inflammation. Int J Obes (Lond). 2010 Feb;34(2):295-301. doi: 10.1038/ijo.2009.220. Epub 2009 Oct 27. PubMed PMID: 19859075.

96: Toms TE, Panoulas VF, Douglas KM, Griffiths H, Sattar N, Smith JP, Symmons DP, Nightingale P, Metsios GS, Kitas GD. Statin use in rheumatoid arthritis in relation to actual cardiovascular risk: evidence for substantial undertreatment of lipid-associated cardiovascular risk? Ann Rheum Dis. 2010 Apr;69(4):683-8. doi: 10.1136/ard.2009.115717. Epub 2009 Oct 23. PubMed PMID: 19854705.

97: Verstappen SM, McCoy MJ, Roberts C, Dale NE, Hassell AB, Symmons DP; STIVEA investigators. Beneficial effects of a 3-week course of intramuscular glucocorticoid injections in patients with very early inflammatory polyarthritis: results of the STIVEA trial. Ann Rheum Dis. 2010 Mar;69(3):503-9. doi: 10.1136/ard.2009.119149. Epub 2009 Oct 12. PubMed PMID: 19825849.

98: Panoulas VF, Smith JP, Stavropoulos-Kalinoglou A, Douglas KM, Nightingale P, Kitas GD. Lack of an association of GNB3 C825T polymorphism and blood pressure in patients with rheumatoid arthritis. Clin Exp Hypertens. 2009 Jul;31(5):428-39. PubMed PMID: 19811352.

99: Panoulas VF, Toms TE, Metsios GS, Stavropoulos-Kalinoglou A, Kosovitsas A, Milionis HJ, Douglas KM, John H, Kitas GD. Target organ damage in patients with rheumatoid arthritis: the role of blood pressure and heart rate. Atherosclerosis. 2010 Mar;209(1):255-60. doi: 10.1016/j.atherosclerosis.2009.08.047. Epub 2009 Aug 31. PubMed PMID: 19781703.

100: Peters MJ, Symmons DP, McCarey D, Dijkmans BA, Nicola P, Kvien TK, McInnes IB, Haentzschel H, Gonzalez-Gay MA, Provan S, Semb A, Sidiropoulos P, Kitas G, Smulders YM, Soubrier M, Szekanecz Z, Sattar N, Nurmohamed MT. EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis. Ann Rheum Dis. 2010 Feb;69(2):325-31. doi: 10.1136/ard.2009.113696. Epub 2009 Sep 22. PubMed PMID: 19773290.

101: Toms TE, Symmons DP, Kitas GD. Dyslipidaemia in rheumatoid arthritis: the role of inflammation, drugs, lifestyle and genetic factors. Curr Vasc Pharmacol. 2010 May;8(3):301-26. Review. PubMed PMID: 19758115.

102: Gasparyan AY, Stavropoulos-Kalinoglou A, Mikhailidis DP, Toms TE, Douglas KM, Kitas GD. The rationale for comparative studies of accelerated atherosclerosis in rheumatic diseases. Curr Vasc Pharmacol. 2010 Jul;8(4):437-49. Review. PubMed PMID: 19758114.

103: McClure A, Lunt M, Eyre S, Ke X, Thomson W, Hinks A, Bowes J, Gibbons L, Plant D, Wilson AG, Marinou I, Morgan AW, Emery P; BIRAC consortium, Steer S, Hocking LJ, Reid DM, Wordsworth P, Harrison P, Worthington J, Barton A. Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci. Rheumatology (Oxford). 2009 Nov;48(11):1369-74. doi: 10.1093/rheumatology/kep272. Epub 2009 Sep 9. Erratum in: Rheumatology (Oxford). 2011 Jun;50(6):1178. PubMed PMID: 19741008; PubMed Central PMCID: PMC2762544.

104: Hyrich KL, Deighton C, Watson KD; BSRBR Control Centre Consortium, Symmons DP, Lunt M; British Society for Rheumatology Biologics Register. Benefit of anti-TNF therapy in rheumatoid arthritis patients with moderate disease activity. Rheumatology (Oxford). 2009 Oct;48(10):1323-7. doi: 10.1093/rheumatology/kep242. Epub 2009 Aug 25. PubMed PMID: 19706737; PubMed Central PMCID: PMC2744336.

105: Phillips DC, Dias HK, Kitas GD, Griffiths HR. Aberrant reactive oxygen and nitrogen species generation in rheumatoid arthritis (RA): causes and consequences for immune function, cell survival, and therapeutic intervention. Antioxid Redox Signal. 2010 Mar 15;12(6):743-85. doi: 10.1089/ars.2009.2607. Review. PubMed PMID: 19686039.

106: Toms TE, Smith JP, Panoulas VF, Douglas KM, Saratzis AN, Kitas GD. Prevalence of risk factors for statin-induced myopathy in rheumatoid arthritis patients. Musculoskeletal Care. 2010 Mar;8(1):2-9. doi: 10.1002/msc.160. PubMed PMID: 19642078.

107: Daoussis D, Panoulas V, Toms T, John H, Antonopoulos I, Nightingale P, Douglas KM, Klocke R, Kitas GD. Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis. Arthritis Res Ther. 2009;11(4):R116. doi: 10.1186/ar2775. Epub 2009 Jul 24. PubMed PMID: 19630964; PubMed Central PMCID: PMC2745798.

108: Saratzis A, Kitas GD, Saratzis N, Melas N. Can statins suppress the development of abdominal aortic aneurysms? A review of the current evidence. Angiology. 2010 Feb;61(2):137-44. doi: 10.1177/0003319709335514. Epub 2009 Jul 21. Review. PubMed PMID: 19625274.

109: Stamatelopoulos KS, Kitas GD, Papamichael CM, Chryssohoou E, Kyrkou K, Georgiopoulos G, Protogerou A, Panoulas VF, Sandoo A, Tentolouris N, Mavrikakis M, Sfikakis PP. Atherosclerosis in rheumatoid arthritis versus diabetes: a comparative study. Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1702-8. doi: 10.1161/ATVBAHA.109.190108. Epub 2009 Jul 16. PubMed PMID: 19608975.

110: Toms TE, Panoulas VF, John H, Douglas KM, Kitas GD. Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60- more than just an anti-inflammatory effect? A cross sectional study. Arthritis Res Ther. 2009;11(4):R110. doi: 10.1186/ar2765. Epub 2009 Jul 16. PubMed PMID: 19607680; PubMed Central PMCID: PMC2745792.

111: Sandoo A, Toms T, Zanten JV, Carroll D, Kitas G. Short-term effects of rituximab on flow-mediated dilatation may be mediated by intravenous glucocorticoids: comment on the article by Gonzalez-Juanatey et al. Arthritis Rheum. 2009 Jun 15;61(6):854-5; author reply 855-6. doi: 10.1002/art.24582. PubMed PMID: 19479694.

112: Burr ML, Naseem H, Hinks A, Eyre S, Gibbons LJ, Bowes J, Wilson AG, Maxwell J, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Thomson W, Worthington J; BIRAC Consortium; YEAR Consortium, Barton A. PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population. Ann Rheum Dis. 2010 Apr;69(4):666-70. doi: 10.1136/ard.2009.111294. Epub 2009 May 25. Erratum in: Ann Rheum Dis. 2011 Aug;70(8):1519. PubMed PMID: 19470526; PubMed Central PMCID: PMC2927647.

113: John H, Treharne GJ, Hale ED, Panoulas VF, Carroll D, Kitas GD. Development and initial validation of a heart disease knowledge questionnaire for people with rheumatoid arthritis. Patient Educ Couns. 2009 Oct;77(1):136-43. doi: 10.1016/j.pec.2009.03.014. Epub 2009 Apr 22. PubMed PMID: 19395226.

114: Panoulas VF, Douglas KM, Smith JP, Metsios GS, Elisaf MS, Nightingale P, Kitas GD. Galectin-2 (LGALS2) 3279C/T polymorphism may be independently associated with diastolic blood pressure in patients with rheumatoid arthritis. Clin Exp Hypertens. 2009 Apr;31(2):93-104. doi: 10.1080/10641960802621267. PubMed PMID: 19330599.

115: Daoussis D, Panoulas VF, Antonopoulos I, John H, Toms TE, Wong P, Nightingale P, Douglas KM, Kitas GD. Cardiovascular risk factors and not disease activity, severity or therapy associate with renal dysfunction in patients with rheumatoid arthritis. Ann Rheum Dis. 2010 Mar;69(3):517-21. doi: 10.1136/ard.2008.105049. Epub 2009 Mar 10. PubMed PMID: 19279016.

116: Metsios GS, Stavropoulos-Kalinoglou A, Panoulas VF, Wilson M, Nevill AM, Koutedakis Y, Kitas GD. Association of physical inactivity with increased cardiovascular risk in patients with rheumatoid arthritis. Eur J Cardiovasc Prev Rehabil. 2009 Apr;16(2):188-94. doi: 10.1097/HJR.0b013e3283271ceb. PubMed PMID: 19238083.

117: John H, Kitas G, Toms T, Goodson N. Cardiovascular co-morbidity in early rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2009 Feb;23(1):71-82. doi: 10.1016/j.berh.2008.11.007. Review. PubMed PMID: 19233047.

118: Lunt M, Solomon D, Rothman K, Glynn R, Hyrich K, Symmons DP, Stürmer T; British Society for Rheumatology Biologics Register; British Society for Rheumatology Biologics Register Control Centre Consortium. Different methods of balancing covariates leading to different effect estimates in the presence of effect modification. Am J Epidemiol. 2009 Apr 1;169(7):909-17. doi: 10.1093/aje/kwn391. Epub 2009 Jan 19. PubMed PMID: 19153216; PubMed Central PMCID: PMC2656533.

119: Panoulas VF, Smith JP, Nightingale P, Kitas GD. Association of the TRAF1/C5 locus with increased mortality, particularly from malignancy or sepsis, in patients with rheumatoid arthritis. Arthritis Rheum. 2009 Jan;60(1):39-46. doi: 10.1002/art.24176. PubMed PMID: 19116907.

120: Panoulas VF, Douglas KM, Smith JP, Stavropoulos-Kalinoglou A, Metsios GS, Nightingale P, Kitas GD. Transforming growth factor-beta1 869T/C, but not interleukin-6 -174G/C, polymorphism associates with hypertension in rheumatoid arthritis. Rheumatology (Oxford). 2009 Feb;48(2):113-8. doi: 10.1093/rheumatology/ken443. Epub 2008 Dec 23. PubMed PMID: 19106168.

121: Stavropoulos-Kalinoglou A, Metsios GS, Panoulas VF, Nevill AM, Jamurtas AZ, Koutedakis Y, Kitas GD. Underweight and obese states both associate with worse disease activity and physical function in patients with established rheumatoid arthritis. Clin Rheumatol. 2009 Apr;28(4):439-44. doi: 10.1007/s10067-008-1073-z. Epub 2008 Dec 19. PubMed PMID: 19096748.

122: Toms TE, Panoulas VF, Douglas KM, Griffiths HR, Kitas GD. Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther. 2008;10(6):R145. doi: 10.1186/ar2578. Epub 2008 Dec 17. PubMed PMID: 19091101; PubMed Central PMCID: PMC2656250.

123: Panoulas VF, Stavropoulos-Kalinoglou A, Metsios GS, Smith JP, Milionis HJ, Douglas KM, Nightingale P, Kitas GD. Association of interleukin-6 (IL-6)-174G/C gene polymorphism with cardiovascular disease in patients with rheumatoid arthritis: the role of obesity and smoking. Atherosclerosis. 2009 May;204(1):178-83. doi: 10.1016/j.atherosclerosis.2008.08.036. Epub 2008 Sep 6. PubMed PMID: 18848327.

124: Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons LJ; Wellcome Trust Case Control Consortium; YEAR Consortium; BIRAC Consortium, Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Worthington J. Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat Genet. 2008 Oct;40(10):1156-9. doi: 10.1038/ng.218. Epub 2008 Sep 14. PubMed PMID: 18794857; PubMed Central PMCID: PMC2662493.

125: Panoulas VF, Ahmad N, Fazal AA, Kassamali RH, Nightingale P, Kitas GD, Labib M. The inter-operator variability in measuring waist circumference and its potential impact on the diagnosis of the metabolic syndrome. Postgrad Med J. 2008 Jul;84(993):344-7. doi: 10.1136/pgmj.2008.068825. PubMed PMID: 18716012.

126: Stavropoulos-Kalinoglou A, Metsios GS, Panoulas VF, Douglas KM, Nevill AM, Jamurtas AZ, Kita M, Koutedakis Y, Kitas GD. Associations of obesity with modifiable risk factors for the development of cardiovascular disease in patients with rheumatoid arthritis. Ann Rheum Dis. 2009 Feb;68(2):242-5. doi: 10.1136/ard.2008.095596. Epub 2008 Aug 3. PubMed PMID: 18677010.

127: Panoulas VF, Douglas KM, Smith JP, Taffé P, Stavropoulos-Kalinoglou A, Toms TE, Elisaf MS, Nightingale P, Kitas GD. Polymorphisms of the endothelin-1 gene associate with hypertension in patients with rheumatoid arthritis. Endothelium. 2008 Jul-Aug;15(4):203-12. doi: 10.1080/10623320802228708. PubMed PMID: 18663623.

128: Stavropoulos-Kalinoglou A, Metsios GS, Panoulas VF, Douglas KM, Nevill AM, Jamurtas AZ, Kita M, Koutedakis Y, Kitas GD. Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study. Arthritis Res Ther. 2008;10(3):R59. doi: 10.1186/ar2429. Epub 2008 May 20. PubMed PMID: 18492239; PubMed Central PMCID: PMC2483449.

129: Panoulas VF, Metsios GS, Pace AV, John H, Treharne GJ, Banks MJ, Kitas GD. Hypertension in rheumatoid arthritis. Rheumatology (Oxford). 2008 Sep;47(9):1286-98. doi: 10.1093/rheumatology/ken159. Epub 2008 May 8. Review. Erratum in: Rheumatology (Oxford). 2009 Apr;48(4):458. PubMed PMID: 18467370.

130: Metsios GS, Stavropoulos-Kalinoglou A, Panoulas VF, Koutedakis Y, Nevill AM, Douglas KM, Kita M, Kitas GD. New resting energy expenditure prediction equations for patients with rheumatoid arthritis. Rheumatology (Oxford). 2008 Apr;47(4):500-6. doi: 10.1093/rheumatology/ken022. Epub 2008 Feb 27. PubMed PMID: 18304942.

131: Panoulas VF, Nikas SN, Smith JP, Douglas KM, Nightingale P, Milionis HJ, Treharne GJ, Toms TE, Kita MD, Kitas GD. Lymphotoxin 252A>G polymorphism is common and associates with myocardial infarction in patients with rheumatoid arthritis. Ann Rheum Dis. 2008 Nov;67(11):1550-6. doi: 10.1136/ard.2007.082594. Epub 2008 Jan 29. PubMed PMID: 18230628.

132: Veldhuijzen van Zanten JJ, Kitas GD. Inflammation, carotid intima-media thickness and atherosclerosis in rheumatoid arthritis. Arthritis Res Ther. 2008;10(1):102. doi: 10.1186/ar2345. Epub 2008 Jan 16. PubMed PMID: 18226183; PubMed Central PMCID: PMC2374455.

133: Panoulas VF, Douglas KM, Stavropoulos-Kalinoglou A, Metsios GS, Nightingale P, Kita MD, Elisaf MS, Kitas GD. Long-term exposure to medium-dose glucocorticoid therapy associates with hypertension in patients with rheumatoid arthritis. Rheumatology (Oxford). 2008 Jan;47(1):72-5. PubMed PMID: 18077493.

134: Metsios GS, Stavropoulos-Kalinoglou A, Veldhuijzen van Zanten JJ, Treharne GJ, Panoulas VF, Douglas KM, Koutedakis Y, Kitas GD. Rheumatoid arthritis, cardiovascular disease and physical exercise: a systematic review. Rheumatology (Oxford). 2008 Mar;47(3):239-48. Epub 2007 Nov 28. Review. PubMed PMID: 18045810.

135: Metsios GS, Stavropoulos-Kalinoglou A, Douglas KM, Koutedakis Y, Nevill AM, Panoulas VF, Kita M, Kitas GD. Blockade of tumour necrosis factor-alpha in rheumatoid arthritis: effects on components of rheumatoid cachexia. Rheumatology (Oxford). 2007 Dec;46(12):1824-7. PubMed PMID: 18032540.

136: Panoulas VF, Douglas KM, Milionis HJ, Nightingale P, Kita MD, Klocke R, Metsios GS, Stavropoulos-Kalinoglou A, Elisaf MS, Kitas GD. Serum uric acid is independently associated with hypertension in patients with rheumatoid arthritis. J Hum Hypertens. 2008 Mar;22(3):177-82. Epub 2007 Oct 25. PubMed PMID: 17960169.

137: Veldhuijzen van Zanten JJ, Kitas GD, Carroll D, Ring C. Increase in systemic vascular resistance during acute mental stress in patients with rheumatoid arthritis with high-grade systemic inflammation. Biol Psychol. 2008 Jan;77(1):106-10. Epub 2007 Sep 11. PubMed PMID: 17949887.

138: Choy EH, Smith CM, Farewell V, Walker D, Hassell A, Chau L, Scott DL; CARDERA (Combination Anti-Rheumatic Drugs in Early Rheumatoid Arhritis) Trial Group. Factorial randomised controlled trial of glucocorticoids and combination disease modifying drugs in early rheumatoid arthritis. Ann Rheum Dis. 2008 May;67(5):656-63. Epub 2007 Sep 3. PubMed PMID: 17768173.

139: John H, Hale ED, Treharne GJ, Kitas GD. Patient education on cardiovascular aspects of rheumatoid disease: an unmet need. Rheumatology (Oxford). 2007 Oct;46(10):1513-6. Epub 2007 Aug 22. PubMed PMID: 17715173.

140: Panoulas VF, Douglas KM, Milionis HJ, Stavropoulos-Kalinglou A, Nightingale P, Kita MD, Tselios AL, Metsios GS, Elisaf MS, Kitas GD. Prevalence and associations of hypertension and its control in patients with rheumatoid arthritis. Rheumatology (Oxford). 2007 Sep;46(9):1477-82. Epub 2007 Aug 17. PubMed PMID: 17704521.

141: Panoulas VF, Milionis HJ, Douglas KM, Nightingale P, Kita MD, Klocke R, Elisaf MS, Kitas GD. Association of serum uric acid with cardiovascular disease in rheumatoid arthritis. Rheumatology (Oxford). 2007 Sep;46(9):1466-70. Epub 2007 Jul 21. PubMed PMID: 17644822.

142: Treharne GJ, Douglas KM, Iwaszko J, Panoulas VF, Hale ED, Mitton DL, Piper H, Erb N, Kitas GD. Polypharmacy among people with rheumatoid arthritis: the role of age, disease duration and comorbidity. Musculoskeletal Care. 2007 Dec;5(4):175-90. PubMed PMID: 17623274.

143: Metsios GS, Stavropoulos-Kalinoglou A, Nevill AM, Douglas KM, Koutedakis Y, Kitas GD. Cigarette smoking significantly increases basal metabolic rate in patients with rheumatoid arthritis. Ann Rheum Dis. 2008 Jan;67(1):70-3. PubMed PMID: 17502358.

144: Piper H, Douglas KM, Treharne GJ, Mitton DL, Haider S, Kitas GD. Prevalence and predictors of ocular manifestations of RA: is there a need for routine screening? Musculoskeletal Care. 2007 Jun;5(2):102-17. PubMed PMID: 17457954.

145: Stavropoulos-Kalinoglou A, Metsios GS, Koutedakis Y, Nevill AM, Douglas KM, Jamurtas A, van Zanten JJ, Labib M, Kitas GD. Redefining overweight and obesity in rheumatoid arthritis patients. Ann Rheum Dis. 2007 Oct;66(10):1316-21. Epub 2007 Feb 8. PubMed PMID: 17289757; PubMed Central PMCID: PMC1994320.

146: Sandhu RS, Treharne GJ, Douglas KM, Cassim K, Saratzis A, Piper H, Erb N, Jenkins D, Tavakoli M, Deighton C, Kitas GD. The impact of anti-tumour necrosis factor therapy for rheumatoid arthritis on the use of other drugs and hospital resources in a pragmatic setting. Musculoskeletal Care. 2006 Dec;4(4):204-22. PubMed PMID: 17117445.

147: Booth DA, Treharne GJ, Kitas GD, Kumar S. Avoidance of unhealthy fattening: a longstanding proposal. Appetite. 2007 Mar;48(2):129-34. Epub 2006 Oct 19. Review. PubMed PMID: 17055110.

148: Witney AG, Treharne GJ, Tavakoli M, Lyons AC, Vincent K, Scott DL, Kitas GD. The relationship of medical, demographic and psychosocial factors to direct and indirect health utility instruments in rheumatoid arthritis. Rheumatology (Oxford). 2006 Aug;45(8):975-81. Epub 2006 Feb 3. PubMed PMID: 16461437.

149: Griffiths HR, Aldred S, Dale C, Nakano E, Kitas GD, Grant MG, Nugent D, Taiwo FA, Li L, Powers HJ. Homocysteine from endothelial cells promotes LDL nitration and scavenger receptor uptake. Free Radic Biol Med. 2006 Feb 1;40(3):488-500. Epub 2005 Nov 15. PubMed PMID: 16443164.

150: Douglas KM, Pace AV, Treharne GJ, Saratzis A, Nightingale P, Erb N, Banks MJ, Kitas GD. Excess recurrent cardiac events in rheumatoid arthritis patients with acute coronary syndrome. Ann Rheum Dis. 2006 Mar;65(3):348-53. Epub 2005 Aug 3. PubMed PMID: 16079169; PubMed Central PMCID: PMC1798075.

151: Stevens RJ, Douglas KM, Saratzis AN, Kitas GD. Inflammation and atherosclerosis in rheumatoid arthritis. Expert Rev Mol Med. 2005 May 6;7(7):1-24. Review. PubMed PMID: 15876361.

152: Raza K, Banks M, Kitas GD. Reversing myocardial microvascular disease in a patient with rheumatoid arthritis. J Rheumatol. 2005 Apr;32(4):754-6. PubMed PMID: 15801038.

153: Veldhuijzen van Zanten JJ, Ring C, Carroll D, Kitas GD. Increased C reactive protein in response to acute stress in patients with rheumatoid arthritis. Ann Rheum Dis. 2005 Sep;64(9):1299-304. Epub 2005 Feb 11. PubMed PMID: 15708880; PubMed Central PMCID: PMC1755638.

154: Raza K, Breese M, Nightingale P, Kumar K, Potter T, Carruthers DM, Situnayake D, Gordon C, Buckley CD, Salmon M, Kitas GD. Predictive value of antibodies to cyclic citrullinated peptide in patients with very early inflammatory arthritis. J Rheumatol. 2005 Feb;32(2):231-8. PubMed PMID: 15693082; PubMed Central PMCID: PMC3160476.

155: Treharne GJ, Batt B, Hale ED, Witney AG, Gordhan C, Situnayake D, Rankin E, Kitas GD, Bacon PA. Assessing patient, carer and healthcare professional education provided by the Birmingham Arthritis Resource Centre (BARC). Rheumatology (Oxford). 2004 Dec;43(12):1594-5; author reply 1595-6. PubMed PMID: 15564644.

156: Treharne GJ, Hale ED, Lyons AC, Booth DA, Banks MJ, Erb N, Douglas KM, Mitton DL, Kitas GD. Cardiovascular disease and psychological morbidity among rheumatoid arthritis patients. Rheumatology (Oxford). 2005 Feb;44(2):241-6. Epub 2004 Nov 2. PubMed PMID: 15522922.

157: Erb N, Pace AV, Douglas KM, Banks MJ, Kitas GD. Risk assessment for coronary heart disease in rheumatoid arthritis and osteoarthritis. Scand J Rheumatol. 2004;33(5):293-9. PubMed PMID: 15513676.

158: Mattey DL, Dawes PT, Nixon NB, Goh L, Banks MJ, Kitas GD. Increased levels of antibodies to cytokeratin 18 in patients with rheumatoid arthritis and ischaemic heart disease. Ann Rheum Dis. 2004 Apr;63(4):420-5. PubMed PMID: 15020337; PubMed Central PMCID: PMC1754968.

159: Bevan RJ, Durand MF, Hickenbotham PT, Kitas GD, Patel PR, Podmore ID, Griffiths HR, Waller HL, Lunec J. Validation of a novel ELISA for measurement of MDA-LDL in human plasma. Free Radic Biol Med. 2003 Sep 1;35(5):517-27. PubMed PMID: 12927601.

160: Bacon PA, Stevens RJ, Carruthers DM, Young SP, Kitas GD. Accelerated atherogenesis in autoimmune rheumatic diseases. Autoimmun Rev. 2002 Dec;1(6):338-47. Review. PubMed PMID: 12848989.

161: Bacon PA, Raza K, Banks MJ, Townend J, Kitas GD. The role of endothelial cell dysfunction in the cardiovascular mortality of RA. Int Rev Immunol. 2002 Jan-Feb;21(1):1-17. Review. PubMed PMID: 12187841.

162: Erb N, Kitas GD. Homocysteine modulation as a reason for continuous folic acid supplementation in methotrexate-treated rheumatoid arthritis patients. Rheumatology (Oxford). 2001 Jun;40(6):715-6. PubMed PMID: 11426040.

163: Kitas G, Banks MJ, Bacon PA. Cardiac involvement in rheumatoid disease. Clin Med. 2001 Jan-Feb;1(1):18-21. Review. PubMed PMID: 11358070.

164: Banks M, Kitas G. Patients’ physical disability may influence doctors’ perceptions of suitability for risk assessment of CHD. BMJ. 1999 Nov 6;319(7219):1266-7. PubMed PMID: 10550104; PubMed Central PMCID: PMC1117033.

165: Situnayake RD, Kitas G. Dyslipidemia and rheumatoid arthritis. Ann Rheum Dis. 1997 Jun;56(6):341-2. PubMed PMID: 9227161; PubMed Central PMCID: PMC1752397.

166: Exley AR, Bacon PA, Luqmani RA, Kitas GD, Gordon C, Savage CO, Adu D. Development and initial validation of the Vasculitis Damage Index for the standardized clinical assessment of damage in the systemic vasculitides. Arthritis Rheum. 1997 Feb;40(2):371-80. PubMed PMID: 9041949.

167: Exley AR, Carruthers DM, Luqmani RA, Kitas GD, Gordon C, Janssen BA, Savage CO, Bacon PA. Damage occurs early in systemic vasculitis and is an index of outcome. QJM. 1997 Jun;90(6):391-9. PubMed PMID: 9205677.

168: Exley AR, Bacon PA, Luqmani RA, Kitas GD, Carruthers DM, Moots R. Examination of disease severity in systemic vasculitis from the novel perspective of damage using the vasculitis damage index (VDI). Br J Rheumatol. 1998 Jan;37(1):57-63. PubMed PMID: 9487252.

169: Bacons PA, Kitas GD. The significance of vascular inflammation in rheumatoid arthritis. Ann Rheum Dis. 1994 Oct;53(10):621-3. Review. PubMed PMID: 7979572; PubMed Central PMCID: PMC1005422.

170: Kalos A, Germenis A, Prountzos P, Kitas GD, Kalodiki E, Fertakis A, Balas P. Complement activation in atherosclerosis: effect of angiography and surgery. Int Angiol. 1988 Jan-Mar;7(1):71-4. PubMed PMID: 2968427.