Relevant Publications

  1. Dessein PH, Tsang L, Norton GR, Woodiwiss AJ, Solomon A. Retinol binding protein 4 concentrations relate to enhanced atherosclerosis in obese patients with rheumatoid arthritis. PLoS One 2014;9:e92738. doi:10.137/journal.pone.0092739. eCollection 2014.
  2. Dessein PH, Norton GR, Woodiwiss AJ, Tsang L. Age impacts on the independent relationships of leptin with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in black and white patients with rheumatoid arthritis: a cross-sectional study. Rheumatol Int 2014;34:329-339.
  3. Dessein PH, López-Mejias R, González-Juanatey C, Genre F, Miranda-Filloy JA, Llorca J, González-Gay MA. Independent Relationship of Osteoprotegerin Concentrations with Endothelial Activation and Carotid Atherosclerosis in Patients with Severe Rheumatoid Arthritis. J Rheumatol 2014;41:429-436..
  4. Dessein PH, Solomon A, Woodiwiss AJ, Norton GR, Tsang L, Gonzalez-Gay MA. Marked Independent Relationship between Circulating Interleukin-6 Concentrations and Endothelial Activation in Rheumatoid Arthritis. Mediators Inflamm 2013 doi.10.1155/2013/510243.
  5. Dessein PH, Solomon A. Towards the elucidation of the true impact of adipocytokines on cardiovascular risk in rheumatoid arthritis. Arthritis Res Ther 2013;15:127.
  6. Dessein PH, Woodiwiss AJ, Norton GR, Tsang L, Solomon A. Independent associations of total and high molecular weight adiponectin with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in black and white patients with rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther 2013;15:R128.
  7. Dessein PH. Vitamin D replacement therapy: a promising adjunct in cardiovascular risk management among patients with rheumatoid arthritis? J Rheumatol 2013;40:1463-1465.
  8. Dessein PH, Woodiwiss AJ, Norton GR, Solomon A. Rheumatoid arthritis is associated with reduced adiposity but not with unfavorable major cardiovascular risk factor profiles and enhanced carotid atherosclerosis in black Africans from a developing population: a cross-sectional study. Arthritis Res Ther 2013;15: R96 [Epub ahead of print].
  9. Dessein PH, Semb AG. Could cardiovascular disease risk stratification and management in rheumatoid arthritis be enhanced? Ann Rheum Dis 2013;72:1743-1746.
  10. Dessein PH, Norton GR, Woodiwiss AJ, Solomon A. Independent relationship between circulating resistin concentrations and endothelial activation in rheumatoid arthritis. Ann Rheum Dis 2013;72:1586-1588
  11. Dessein PH, Norton GR, Badenhorst M, Woodiwiss AJ, Solomon A. Rheumatoid arthritis impacts on the independent relationships between circulating adiponectin concentrations and cardiovascular metabolic risk. Mediators Inflamm 2013;2013:461849.doi.10.1155/2013/461849.
  12. Gonzalez-Gay MA, Szekanecz Z, Popa CD, Dessein P. Atherosclerosis in rheumatoid arthritis. Mediators Inflamm 2012;2012:489608. doi:10.1155/2012/489608. Epub 2012 Oct 17.
  13. Dessein PH, Norton GR, Joffe BI, Abdool-Carrim AT, Woodiwiss AJ, Solomon A. Metabolic cardiovascular risk burden and atherosclerosis in African black and Caucasian women with rheumatoid arthritis: a cross-sectional study. Clin Exp Rheumatol 2013;31:53-61.
  14. Solomon A, Woodiwiss AJ, Abdool-Carrim AT, Stevens BA, Norton GR, Dessein PH. The carotid artery atherosclerosis burden and its associated cardiovascular risk factors in black and white Africans with rheumatoid arthritis:a cross-sectional study. J Rheumatol 2012;39:1798-1806.
  15. Solomon A, Norton GR, Woodiwiss AJ, Dessein PH. Obesity and carotid atherosclerosis in African black and Caucasian women with established rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther 2012, 14:R67.
  16. Dessein PH, Christian BF, Woodiwiss AJ, Norton GR, Solomon A. Public healthcare attendance associates with enhanced conventional and non-conventional atherosclerotic cardiovascular disease risk burdens in established rheumatoid arthritis. Clin Exp Rheumatol 2010;28:230-237.
  17. Solomon A, Christian BF, Norton GR, Woodiwiss AJ, Dessein PH. Risk factor profiles for atherosclerotic cardiovascular disease in Black and other Africans with established rheumatoid arthritis. J Rheumatol 2010;37:953-960.
  18. Dessein PH, Christian BF, Solomon A. Application of the Joint British Societies’ guidelines on the prevention of cardiovascular disease in public and private health care patients with rheumatoid arthritis. J Rheumatol 2010;37:201-202.
  19. Gonzalez-Gay MA, Garcia-Unzueta MT, Berja A, Vazquez-Rodriguez TR, Miranda-Filloy JA, Gonzalez-Juanatey C, de Matias JM, Martin J, Dessein PH, Llorca J. Short-term effect of anti-TNF-alpha therapy on nitric oxide production in patients with severe rheumatoid arthritis. Clin Exp Rheumatol 2009;27:452-458.
  20. Dessein PH, Christian BF, Solomon A. Which are the determinants of dyslipidemia in rheumatoid arthritis and does socioeconomic status matter in this context? J Rheumatol 2009;36:1357-1361.
  21. Gonzalez-Gay MA, Garcia-Unzueta MT, Berja A, Gonzalez-Juanatey C, Miranda-Filloy JA, Vazquez-Rodriguez TR, de Matias JM, Martin J, Dessein PH, Llorca J. Anti-TNF-alpha therapy does not modulate leptin in patients with severe rheumatoid arthritis. Clin Exp Rheumatol 2009;27:222-228.
  22. Gonzalez-Gay MA, Garcia-Unzueta MT, Berja A, Vazquez-Rodriguez TR, Gonzalez-Juanatey C, de Matias JM, Martin J, Dessein PH, Llorca J. Anti-tumor necrosis factor alpha therapy modulates ghrelin patients with severe rheumatoid arthritis. Ann Rheum Dis 2008;67:1644-1646.
  23. Gonzalez-Gay M, Llorca J, Garcia-Unzueta MT, Gonzalez-Juanatey C, De Matias JM, Martin J, Redelinghuys M, Woodiwiss AJ, Norton GR, Dessein PH. High-grade inflammation, circulating adiponectin concentrations and cardiovascular risk factors in severe rheumatoid arthritis. Clin Exp Rheumatol 2008;26:596-603.
  24. Dessein PH, Norton GR. Should patients with RA be aggressively monitored for hypertension? Nature Clin Pract Rheumatol 2008;4:18-19.
  25. Gonzalez-Gay M, Garcia-Unzueta M, Gonzalez-Juanatey C, Miranda-Filloy J, De Matias J, Martin J, Dessein P, Llorca J. Anti-TNF-alpha therapy modulates resistin in patients with rheumatoid arthritis. Clin Exp Rheumatol 2008;26:311-316.
  26. Dessein PH, Woodiwiss AJ, Joffe BI, Norton GR. Aminotransferases are associated with insulin resistance and atherosclerosis in rheumatoid arthritis. BMC Cardiovasc Disord 2007;7(1):31.
  27. Dessein PH, Norton GR, Woodiwiss AJ, Joffe BI, Wolfe F. Influence of nonclassical cardiovascular risk factors on the accuracy of predicting subclinical atherosclerosis in rheumatoid arthritis. J Rheumatol 2007;34:943-951.
  28. Dessein PH, Norton GR, Woodiwiss AJ, Joffe BI, Solomon A. Independent role of conventional cardiovascular risk factors as predictors of C-reactive protein concentrations in rheumatoid arthritis. J Rheumatol 2007;34:681-688.
  29. Dessein PH, Tobias M, Veller MG. Metabolic syndrome and subclinical atherosclerosis in rheumatoid arthritis. J Rheumatol 2006;33:2425-2432.
  30. Dessein PH, Joffe BI. Insulin resistance and impaired ß-cell function in rheumatoid arthritis. Arthritis Rheum 2006;54: 2765-2775.
  31. Dessein PH, Joffe BI. Suppression of circulating interleukin-6 concentrations is associated with decreased endothelial activation in rheumatoid arthritis. Clin Exp Rheumatol 2006;24:161-167.
  32. Dessein PH, Joffe BI. When is a patient with rheumatoid arthritis at risk for cardiovascular disease? J Rheumatol 2006;33:201-203.
  33. Dessein PH, Joffe BI, Singh S. Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis. Ann Rheum Dis 2005;64:178-179.
  34. Dessein PH, Joffe BI, Stanwix AE. Should we measure insulin sensitivity in rheumatoid arthritis. Semin Arthritis Rheum 2005;35:5-7.
  35. Dessein PH, Joffe BI, Singh S. Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis. Arthritis Res Ther 2005;7:R634-R643.
  36. Dessein PH, Joffe BI, Veller MG, Stevens BA, Tobias M, Reddi K, Stanwix AE. Traditional and non-traditional cardiovascular risk factors are associated with atherosclerosis in rheumatoid arthritis. J Rheumatol 2005;32:435-442.
  37. Dessein PH, Stanwix AE. Steroids and myocardial infarction in rheumatoid arthritis. Reply to Dr AS Russell. J Rheumatol 2005;32:196-197.
  38. Dessein PH, Joffe BI, Stanwix AE. Subclinical hypothyroidism is associated with insulin resistance in rheumatoid arthritis. Thyroid 2004;14:443-446.
  39. Dessein PH, Joffe BI, Stanwix AE. High sensitivity C-reactive protein as a disease activity marker in rheumatoid arthritis. J Rheumatol June 2004;31:1095-1097.
  40. Dessein PH, Joffe BI, Stanwix AE, Christian BF, Veller M. Glucocorticoids and insulin sensitivity in rheumatoid arthritis. J Rheumatol May 2004;31:867-874.
  41. Dessein PH, Joffe BI, Stanwix AE. Inflammation, insulin resistance, and aberrant lipid metabolism as cardiovascular risk factors in rheumatoid arthritis. J Rheumatol 2003;30:1403-1405.
  42. Dessein PH, Joffe BI, Stanwix AE. Effects of disease modifying agents and dietary intervention on insulin resistance and dyslipidemia in inflammatory arthritis – a pilot study. Arthritis Res 2002;4:R12.
  43. Dessein PH, Stanwix AE, Joffe BI. Cardiovascular risk in rheumatoid arthritis versus osteoarthritis: acute phase response related decreased insulin sensitivity and high-density lipoprotein cholesterol as well as clustering of metabolic syndrome features in rheumatoid arthritis. Arthritis Res 2002;4:R5.
  44. Dessein PH, Joffe BI, Stanwix A, Botha AS, Moomal Z. The acute phase response does not fully predict the presence of insulin resistance and dyslipidemia in inflammatory arthritis. J Rheumatol 2002;29:462-466.
  45. Dessein PH, Stanwix AE. Inflammatory arthritis and cardiovascular disease may share a common predisposition. Rheumatology 2001;40:703-704.