Dr. Liao is a clinical investigator and focuses her research on outcomes in rheumatoid arthritis. She is an Assistant Professor of Medicine at Harvard Medical School and is co-director of the Cardiovascular Clinic in Rheumatology at the Brigham and Women’s Arthritis Center. Her current active projects include studies of: (1) cardiovascular disease (CVD) in rheumatoid arthritis (RA), and (2) application of bioinformatics and biostatistics methods for clinical and translational research using electronic medical record (EMR) data.
RA patients are at higher risk for CVD than the general population. Dr. Liao is investigating how inflammation may modify traditional CV risk factors leading to the excess risk in RA. She also studies subphenotypes of RA, e.g. rapid radiologic progressors vs RA pts who do not develop erosions. Through her work with the Informatics for Integrating Biology and the Bedside (i2b2) project, Dr. Liao has developed an EMR research platform for her RA studies using large integrated datasets (e.g. clinical EMR data, genetics, laboratory assays). Using this EMR research platform she applies novel methods from the fields of bioinformatics and biostatistics to study clinical areas of interest such as CVD in RA.